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Study · In vitro (cells) · 1995

1 result

The thymus extract Thymex-L potentiates the retinoic acid-induced differentiation of the human myeloid leukemia cell line HL-60.

Schulze-Forster K, Eckert K, Maurer HR

Biochimica et biophysica acta1 Mar 1995Cited by 2 (Europe PMC)

PMID7696339 (opens in a new tab)DOI10.1016/0167-4889(94)00212-w (opens in a new tab)PepBankPUB-07696339
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study1

1 result from studies that gave the peptide. No result from this study comes from people.

  1. 01LabIn vitro (cells)Activity measurement

    In HL-60 human leukemia cells, thymosin alpha‑1 did not synergistically enhance retinoic acid-induced differentiation.

    In plain wordsIn lab tests on leukemia cells, thymosin alpha‑1 did not boost the effect of retinoic acid on cell maturation.

    Peptide
    Thymosin alpha-1
    Outcome
    No significant changeSynergistic enhancement of RA-induced HL-60 differentiation
    Study

    humann: not reported in source

    HL-60 human promyelocytic leukemia cells
    Outcome group
    Tumor growth · Cancer
    Studied dose
    Dose not stated

    Source sentences

    Summary
    The defined thymus peptides thymosin alpha 1, prothymosin alpha 1 and thymopentin were unable to synergistically enhance HL-60 differentiation.
    1 context sentence
    Summary · context
    The human promyelocytic cell line HL-60 can be differentiated with retinoic acid (RA) along the granulocytic pathway.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 3Current

    10 Oct 2026, 08:55 UTC

    Study results updated

  2. Version 2

    9 Oct 2026, 03:03 UTC

    Study data updated · source update from Europe PMC

  3. Version 1

    9 Oct 2026, 03:02 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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