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Study · Non-randomized trial · n = 18 · 1993

9 results

Effect of growth hormone treatment on hormonal parameters, body composition and strength in athletes.

Deyssig R, Frisch H, Blum WF, Waldhör T

Acta endocrinologica1 Apr 1993Cited by 72 (Europe PMC)

PMID7684551 (opens in a new tab)DOI10.1530/acta.0.1280313 (opens in a new tab)PepBankPUB-07684551
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study9

9 results from studies that gave the peptide. 9 results from people.

  1. 01HumanNon-randomized trialEfficacy outcome

    In male power athletes, GH treatment had no effect on maximal biceps strength during concentric contraction.

    In plain wordsIn male power athletes, GH treatment did not improve maximal biceps strength.

    Peptide
    HGH (somatotropin)
    Outcome
    No significant changeBiceps maximal strength
    Study

    n = 18

    Outcome group
    Exercise and physical function · Musculoskeletal
    Studied dose
    0.09U (kg BW)-1 day-1 · sc · six weeksAs given in this study (human).

    Source sentences

    Summary
    There was no effect of GH treatment on maximal strength during concentric contraction of the biceps and quadriceps muscles.
    3 context sentences
    Summary · context
    The effect of recombinant GH on strength, body composition and endocrine parameters in power athletes was investigated in a controlled study.
    Summary · context
    Probands were assigned in a double-blind manner to either GH treatment (0.09U (kg BW)-1 day-1 sc) or placebo for a period of six weeks.
    Summary · context
    For final evaluation only data of those 8 and 10 subjects in the two groups who completed the study were analyzed.
  2. 02HumanNon-randomized trialEfficacy outcome

    In male power athletes, GH treatment had no effect on maximal quadriceps strength during concentric contraction.

    In plain wordsIn male power athletes, GH treatment did not improve maximal quadriceps strength.

    Peptide
    HGH (somatotropin)
    Outcome
    No significant changeQuadriceps maximal strength
    Study

    n = 18

    Outcome group
    Exercise and physical function · Musculoskeletal
    Studied dose
    0.09U (kg BW)-1 day-1 · sc · six weeksAs given in this study (human).

    Source sentences

    Summary
    There was no effect of GH treatment on maximal strength during concentric contraction of the biceps and quadriceps muscles.
    3 context sentences
    Summary · context
    The effect of recombinant GH on strength, body composition and endocrine parameters in power athletes was investigated in a controlled study.
    Summary · context
    Probands were assigned in a double-blind manner to either GH treatment (0.09U (kg BW)-1 day-1 sc) or placebo for a period of six weeks.
    Summary · context
    For final evaluation only data of those 8 and 10 subjects in the two groups who completed the study were analyzed.
  3. 03HumanNon-randomized trialEfficacy outcome

    In male power athletes, serum GH increased significantly in the GH-treated group.

    In plain wordsIn male power athletes, blood GH increased during GH treatment.

    Peptide
    HGH (somatotropin)
    Outcome
    IncreaseSerum GH
    Study

    n: not reported in source

    Outcome group
    Growth hormone and IGF-1 · Endocrine and hormones
    Studied dose
    0.09U (kg BW)-1 day-1 · sc · six weeksAs given in this study (human).

    Source sentences

    Summary
    GH, IGF-I and IGF-binding protein were in the normal range before therapy and increased significantly in the GH-treated group.
    3 context sentences
    Summary · context
    The effect of recombinant GH on strength, body composition and endocrine parameters in power athletes was investigated in a controlled study.
    Summary · context
    Probands were assigned in a double-blind manner to either GH treatment (0.09U (kg BW)-1 day-1 sc) or placebo for a period of six weeks.
    Summary · context
    For final evaluation only data of those 8 and 10 subjects in the two groups who completed the study were analyzed.
  4. 04HumanNon-randomized trialEfficacy outcome

    In male power athletes, serum IGF-I increased significantly in the GH-treated group.

    In plain wordsIn male power athletes, blood IGF-I increased during GH treatment.

    Peptide
    HGH (somatotropin)
    Outcome
    IncreaseSerum IGF-I
    Study

    n: not reported in source

    Outcome group
    Growth hormone and IGF-1 · Endocrine and hormones
    Studied dose
    0.09U (kg BW)-1 day-1 · sc · six weeksAs given in this study (human).

    Source sentences

    Summary
    GH, IGF-I and IGF-binding protein were in the normal range before therapy and increased significantly in the GH-treated group.
    3 context sentences
    Summary · context
    The effect of recombinant GH on strength, body composition and endocrine parameters in power athletes was investigated in a controlled study.
    Summary · context
    Probands were assigned in a double-blind manner to either GH treatment (0.09U (kg BW)-1 day-1 sc) or placebo for a period of six weeks.
    Summary · context
    For final evaluation only data of those 8 and 10 subjects in the two groups who completed the study were analyzed.
  5. 05HumanNon-randomized trialEfficacy outcome

    In male power athletes, IGF-binding protein increased significantly in the GH-treated group.

    In plain wordsIn male power athletes, an IGF-binding protein increased during GH treatment.

    Peptide
    HGH (somatotropin)
    Outcome
    IncreaseIGF-binding protein
    Study

    n: not reported in source

    Outcome group
    Growth hormone and IGF-1 · Endocrine and hormones
    Studied dose
    0.09U (kg BW)-1 day-1 · sc · six weeksAs given in this study (human).

    Source sentences

    Summary
    GH, IGF-I and IGF-binding protein were in the normal range before therapy and increased significantly in the GH-treated group.
    3 context sentences
    Summary · context
    The effect of recombinant GH on strength, body composition and endocrine parameters in power athletes was investigated in a controlled study.
    Summary · context
    Probands were assigned in a double-blind manner to either GH treatment (0.09U (kg BW)-1 day-1 sc) or placebo for a period of six weeks.
    Summary · context
    For final evaluation only data of those 8 and 10 subjects in the two groups who completed the study were analyzed.
  6. 06HumanNon-randomized trialEfficacy outcome

    In male power athletes receiving GH, fasting insulin increased nonsignificantly.

    In plain wordsIn male power athletes, fasting insulin did not increase significantly during GH treatment.

    Peptide
    HGH (somatotropin)
    Outcome
    No significant changeFasting insulin
    Study

    n: not reported in source

    Outcome group
    Glycemic control · Metabolic and weight
    Studied dose
    0.09U (kg BW)-1 day-1 · sc · six weeksAs given in this study (human).

    Source sentences

    Summary
    Fasting insulin concentrations increased insignificantly and thyroxine levels decreased significantly in the GH-treated probands.
    3 context sentences
    Summary · context
    The effect of recombinant GH on strength, body composition and endocrine parameters in power athletes was investigated in a controlled study.
    Summary · context
    Probands were assigned in a double-blind manner to either GH treatment (0.09U (kg BW)-1 day-1 sc) or placebo for a period of six weeks.
    Summary · context
    For final evaluation only data of those 8 and 10 subjects in the two groups who completed the study were analyzed.
  7. 07HumanNon-randomized trialEfficacy outcome

    In male power athletes receiving GH, thyroxine levels decreased significantly.

    In plain wordsIn male power athletes, thyroxine levels decreased during GH treatment.

    Peptide
    HGH (somatotropin)
    Outcome
    DecreaseThyroxine
    Study

    n: not reported in source

    Outcome group
    Thyroid function · Endocrine and hormones
    Studied dose
    0.09U (kg BW)-1 day-1 · sc · six weeksAs given in this study (human).

    Source sentences

    Summary
    Fasting insulin concentrations increased insignificantly and thyroxine levels decreased significantly in the GH-treated probands.
    3 context sentences
    Summary · context
    The effect of recombinant GH on strength, body composition and endocrine parameters in power athletes was investigated in a controlled study.
    Summary · context
    Probands were assigned in a double-blind manner to either GH treatment (0.09U (kg BW)-1 day-1 sc) or placebo for a period of six weeks.
    Summary · context
    For final evaluation only data of those 8 and 10 subjects in the two groups who completed the study were analyzed.
  8. 08HumanNon-randomized trialEfficacy outcome

    In male power athletes, body weight did not change significantly during GH treatment.

    In plain wordsIn male power athletes, body weight did not change significantly during GH treatment.

    Peptide
    HGH (somatotropin)
    Outcome
    No significant changeBody weight
    Study

    n: not reported in source

    Outcome group
    Body weight · Metabolic and weight
    Studied dose
    0.09U (kg BW)-1 day-1 · sc · six weeksAs given in this study (human).

    Source sentences

    Summary
    Body weight and body fat were not changed significantly during treatment.
    3 context sentences
    Summary · context
    The effect of recombinant GH on strength, body composition and endocrine parameters in power athletes was investigated in a controlled study.
    Summary · context
    Probands were assigned in a double-blind manner to either GH treatment (0.09U (kg BW)-1 day-1 sc) or placebo for a period of six weeks.
    Summary · context
    For final evaluation only data of those 8 and 10 subjects in the two groups who completed the study were analyzed.
  9. 09HumanNon-randomized trialEfficacy outcome

    In male power athletes, body fat did not change significantly during GH treatment.

    In plain wordsIn male power athletes, body fat did not change significantly during GH treatment.

    Peptide
    HGH (somatotropin)
    Outcome
    No significant changeBody fat
    Study

    n: not reported in source

    Outcome group
    Body composition · Metabolic and weight
    Studied dose
    0.09U (kg BW)-1 day-1 · sc · six weeksAs given in this study (human).

    Source sentences

    Summary
    Body weight and body fat were not changed significantly during treatment.
    3 context sentences
    Summary · context
    The effect of recombinant GH on strength, body composition and endocrine parameters in power athletes was investigated in a controlled study.
    Summary · context
    Probands were assigned in a double-blind manner to either GH treatment (0.09U (kg BW)-1 day-1 sc) or placebo for a period of six weeks.
    Summary · context
    For final evaluation only data of those 8 and 10 subjects in the two groups who completed the study were analyzed.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    28 Oct 2026, 02:03 UTC

    Study results updated

  2. Version 1

    27 Oct 2026, 16:37 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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