Study · In vitro (cells) · rat · 1993
5 resultsEstévez MD, Botana MA, Arnáez E, Vieytes MR, Botana LM
International archives of allergy and immunology1 Jan 1993Cited by 3 (Europe PMC)
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Text rights: Publisher copyright. Results still quote short attributed sentences.
3 results from studies that gave the peptide. No result from this study comes from people.
Human GRF(1-29)NH2 elicited histamine release from rat pleural and peritoneal mast cells.
In plain wordsIn rat cells, human GRF(1-29)NH2 made mast cells release histamine.
ratn: not reported in source
rat peritoneal and pleural mast cellsSource sentences
Histamine release on rat pleural and peritoneal mast cells elicited by human GRF(1-29)NH2.
GRF-elicited secretion from rat mast cells was temperature dependent and optimal at 37 degrees C.
In plain wordsIn rat cells, GRF-triggered histamine release depended on temperature and was best at 37 degrees C.
ratn: not reported in source
rat peritoneal and pleural mast cellsSource sentences
The secretion is temperature dependent, the release being optimal at 37 degrees C
Activation by GRF was similar in pleural and peritoneal rat mast cells.
In plain wordsIn rat cells, GRF activated pleural and peritoneal mast cells in a similar way.
ratn: not reported in source
rat peritoneal and pleural mast cellsSource sentences
The activation of pleural and peritoneal mast cells is similar
In this study, Sermorelin was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking Sermorelin.
Antimycin A inhibited GRF-elicited secretion from rat mast cells.
In plain wordsIn rat cells, antimycin A reduced histamine release triggered by GRF.
ratn: not reported in source
rat peritoneal and pleural mast cellsSource sentences
and it can be inhibited with antimycin A.
In this study, Sermorelin was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Sermorelin.
Purification with Percoll slightly inhibited the GRF-induced activation of both pleural and peritoneal rat mast cells.
In plain wordsIn rat cells, purifying the cells with Percoll slightly lowered their response to GRF.
ratn: not reported in source
rat peritoneal and pleural mast cellsSource sentences
but there is a slight inhibition for both populations after purification with Percoll.
In this study, Sermorelin was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Sermorelin.
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Version 2Current
10 Oct 2026, 10:21 UTC
Study results updated
Version 1
9 Oct 2026, 03:13 UTC
First added · source update from Europe PMC
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