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Study · In vitro (cells) · rat · 1995

1 result

Regulation of the pituitary-specific transcription factor GHF-1/Pit-1 messenger ribonucleic acid levels by growth hormone-secretagogues in rat anterior pituitary cells in monolayer culture.

Soto JL, Castrillo JL, Dominguez F, Dieguez C

Endocrinology1 Sept 1995Cited by 35 (Europe PMC)

PMID7649093 (opens in a new tab)DOI10.1210/endo.136.9.7649093 (opens in a new tab)PepBankPUB-07649093
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study1

1 result from studies that gave the peptide. No result from this study comes from people.

  1. 01LabIn vitro (cells)Mechanism

    In cultured rat anterior pituitary cells, GHRP‑6 did not increase GHF-1 mRNA levels.

    In plain wordsIn cells from rat pituitaries, GHRP‑6 did not increase GHF-1 mRNA levels.

    Peptide
    GHRP-6
    Outcome
    No significant changeGHF-1 mRNA
    Study

    ratn: not reported in source

    Primary anterior pituitary cells
    Outcome group
    Receptor activity and mechanism · Endocrine and hormones
    Studied dose
    10(-10) to 10(-5) MAs given in this study (rat).

    Source sentences

    Summary
    Other peptides such as pituitary adenylate cyclase activating polypeptide-38 (10(-7) M) but not GHRP-6 (10(-10) to 10(-5) M), were also able to increase GHF-1 mRNA levels.
    1 context sentence
    Summary · context
    The aim of this study was to investigate the regulation of GHF-1 messenger RNA (mRNA) levels in primary monolayer cultures of rat anterior pituitary cells.

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Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    21 Oct 2026, 15:58 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 03:13 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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