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Study · Not a test of the peptide alone · 1995

3 results

Estrogen-sensitive oxytocin binding sites are differently regulated by progesterone in the telencephalon and the hypothalamus of the rat.

Krémarik P, Freund-Mercier MJ, Stoeckel ME

Journal of neuroendocrinology1 Apr 1995Cited by 16 (Europe PMC)

PMID7647770 (opens in a new tab)DOI10.1111/j.1365-2826.1995.tb00759.x (opens in a new tab)PepBankPUB-07647770
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study3

No result from this study comes from a test of the peptide.

Studies that did not test the peptide alone3

In this study, Oxytocin was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking Oxytocin.

  1. 01AnimalNot a test of Oxytocin aloneAnimal study (in vivo)Mechanism

    In rats, estrogen administration induced expression of oxytocin binding sites in the major island of Calleja, anterior hypothalamic area and terete nucleus.

    In plain wordsIn rats, estrogen increased the number of oxytocin binding sites in several brain areas.

    Peptide
    Oxytocin
    Outcome
    IncreaseEstrogen induction of oxytocin binding sites in brain regions
    Study

    ratn: not reported in source

    castrated and intact male rats and ovariectomized female rats
    Outcome group
    Sex hormones and fertility · Reproductive and sexual health

    Source sentences

    Summary
    Estrogen administration in addition induced expression of oxytocin binding sites in the major island of Calleja, the anterior hypothalamic area and the terete nucleus.
    2 context sentences
    Summary · context
    The localization at the cellular level and the regulation by progesterone of the estrogen-sensitive oxytocin binding sites was studied in the rat telencephalon and the hypothalamus by using quantitative film-autoradiography and histoautoradiography.
    Summary · context
    Male rats (castrated or not) and ovariectomized females (estradiol supplemented or not) were used to characterize these sites and to precise their localization.

    In this study, Oxytocin was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Oxytocin.

  2. 02AnimalNot a test of Oxytocin aloneAnimal study (in vivo)Mechanism

    In rats, the density of estrogen-sensitive oxytocin binding sites varied during the estrous cycle, and the pattern differed between the telencephalon and the hypothalamus.

    In plain wordsIn rats, the number of oxytocin binding sites changed during the estrous cycle, with different patterns in two brain regions.

    Peptide
    Oxytocin
    Outcome
    MixedOxytocin binding site density across the estrous cycle
    Study

    ratn: not reported in source

    female rats during the estrous cycle
    Outcome group
    Sex hormones and fertility · Reproductive and sexual health

    Source sentences

    Summary
    The density of the estrogen-sensitive oxytocin binding sites varied during the estrous cycle, but differently in the telencephalon and the hypothalamus.
    3 context sentences
    Summary · context
    In the telencephalon it peaked at proestrus 9 h and was already decreased at proestrus 21 h
    Summary · context
    The localization at the cellular level and the regulation by progesterone of the estrogen-sensitive oxytocin binding sites was studied in the rat telencephalon and the hypothalamus by using quantitative film-autoradiography and histoautoradiography.
    Summary · context
    Male rats (castrated or not) and ovariectomized females (estradiol supplemented or not) were used to characterize these sites and to precise their localization.

    In this study, Oxytocin was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Oxytocin.

  3. 03AnimalNot a test of Oxytocin aloneAnimal study (in vivo)Mechanism

    In rats, estrogen-sensitive oxytocin binding sites were detected in the striatal cell bridges, olfactory tubercle, bed nucleus of the stria terminalis and medial amygdala of the telencephalon, and in several hypothalamic nuclei.

    In plain wordsIn rats, oxytocin binding sites that respond to estrogen were found in several brain areas.

    Peptide
    Oxytocin
    Outcome
    Not applicableRegional distribution of estrogen-sensitive oxytocin binding sites
    Study

    ratn: not reported in source

    castrated and intact male rats and ovariectomized female rats
    Outcome group
    Sex hormones and fertility · Nervous system and cognition

    Source sentences

    Summary
    They were detected in the striatal cell bridges, the olfactory tubercle, the principal nucleus of the bed nucleus of the stria terminalis and the medial nucleus of the amygdala of the telencephalon and in the medial preoptic, the ventromedial and the ventral premammillary nuclei of the hypothalamus.

    In this study, Oxytocin was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Oxytocin.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    11 Oct 2026, 20:03 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 02:51 UTC

    First added · source update from Europe PMC

Subjects

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