In men born and living at high altitude, the GH response to intravenous GHRH(1-29) was exaggerated compared with men living at sea level.
In plain wordsIn men living at high altitude, growth hormone rose more after GHRH(1-29) than in men living at sea level.
- Peptide
- Sermorelin
- Outcome
- IncreaseGH response to GHRH in high-altitude versus sea-level men
- Study
n = 22
- Comparator
- Men living at sea level
- Outcome group
- Growth hormone and IGF-1 · Endocrine and hormones
- Studied dose
- 1 microgram/kg · intravenousAs given in this study (human).
Source sentences
GH response to GHRH in HA men was exaggerated compared to SL men, and IGF-I concentration was also significantly increased in the presence of normal levels of IGFBP-3.
2 context sentences(design, population, supporting numbers)
Growth hormone releasing hormone (Geref 1-29) 1 microgram/kg, TRH 500 micrograms, GHRH 100 micrograms and ovine corticotrophin releasing hormone (oCRH) 1 microgram/kg were simultaneously administered intravenously
12 born and raised in the city of Pasto, Colombia, South America, located at an altitude of 2600 m in the southern Colombian Andes (HA group) and 10 men living at sea level (SL) in Tampa, Florida.