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Study · Measured the body's own peptide · 1995

3 results

The effect of dietary sodium on the concentrations of vasoactive intestinal peptide in plasma and lung.

Ye VZ, Duggan KA

Chest1 Aug 1995

PMID7634895 (opens in a new tab)DOI10.1378/chest.108.2.535 (opens in a new tab)PepBankPUB-07634895
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study3

No result from this study comes from a test of the peptide.

Natural levels measured3

These results measure the body's own peptide. Nobody was given the peptide. They are not evidence about taking it. They are left out of key results, evidence counts and charts.

  1. 01AnimalEndogenous levelAnimal study (in vivo)Other

    In rats, plasma levels of the body's own VIP were lower on a high-sodium diet than on a low-sodium diet.

    In plain wordsIn rats, a high-sodium diet gave lower natural VIP levels in blood than a low-sodium diet.

    Peptide
    Vasoactive intestinal peptide (VIP, aviptadil)
    Outcome
    DecreasePlasma VIP, low- versus high-sodium diet
    Study

    ratn: not reported in source

    Male Sprague-Dawley rats on low-, normal- or high-sodium diet for 7 days
    Comparator
    Low-sodium diet
    Outcome group
    Endogenous peptide levels · Respiratory

    Measurements

    Plasma VIP
    51.45 pmol L-1
    low-sodium diet
    Plasma VIP
    29.84 pmol L-1
    high-sodium diet

    Source sentences

    Summary
    Plasma VIP level was significantly higher in the rats that had received the low-sodium diet (51.45 +/- 7.35 pmol L-1) than in the rats that had received the high-sodium diet (29.84 +/- 6.83; p < 0.05).
    1 context sentence
    Summary · context
    Male Sprague-Dawley rats, eight in each group, were placed on low-sodium, normal-sodium, or high-sodium diets and distilled drinking water ad libitum for 7 days.

    This result measures the body's own Vasoactive intestinal peptide (VIP, aviptadil). Nobody was given the peptide. It is not evidence about taking it.

  2. 02AnimalEndogenous levelAnimal study (in vivo)Other

    In rats, lung levels of the body's own VIP were lower on a low-sodium diet than on a normal-sodium diet.

    In plain wordsIn rats, a low-sodium diet gave lower natural VIP levels in the lung than a normal-sodium diet.

    Peptide
    Vasoactive intestinal peptide (VIP, aviptadil)
    Outcome
    DecreaseLung VIP, low- versus normal-sodium diet
    Study

    ratn: not reported in source

    Male Sprague-Dawley rats on low-, normal- or high-sodium diet for 7 days
    Comparator
    Normal-sodium diet
    Outcome group
    Endogenous peptide levels · Respiratory

    Measurements

    Lung VIP
    378.13 fmol/g
    normal-sodium diet
    Lung VIP
    137.3 fmol/g
    low-sodium diet

    Source sentences

    Summary
    In the lung, VIP level was greater in the rats that had received the normal-sodium diet (378.13 +/- 41.68 fmol/g) than in rats that had received either the low-sodium diet (137.30 +/- 26.11 fmol/g; p < 0.0005) or the high-sodium diet (182.64 +/- 28.63 fmol/g; p < 0.005).
    1 context sentence
    Summary · context
    Male Sprague-Dawley rats, eight in each group, were placed on low-sodium, normal-sodium, or high-sodium diets and distilled drinking water ad libitum for 7 days.

    This result measures the body's own Vasoactive intestinal peptide (VIP, aviptadil). Nobody was given the peptide. It is not evidence about taking it.

  3. 03AnimalEndogenous levelAnimal study (in vivo)Other

    In rats, lung levels of the body's own VIP were lower on a high-sodium diet than on a normal-sodium diet.

    In plain wordsIn rats, a high-sodium diet gave lower natural VIP levels in the lung than a normal-sodium diet.

    Peptide
    Vasoactive intestinal peptide (VIP, aviptadil)
    Outcome
    DecreaseLung VIP, high- versus normal-sodium diet
    Study

    ratn: not reported in source

    Male Sprague-Dawley rats on low-, normal- or high-sodium diet for 7 days
    Comparator
    Normal-sodium diet
    Outcome group
    Endogenous peptide levels · Respiratory

    Measurements

    Lung VIP
    378.13 fmol/g
    normal-sodium diet
    Lung VIP
    182.64 fmol/g
    high-sodium diet

    Source sentences

    Summary
    In the lung, VIP level was greater in the rats that had received the normal-sodium diet (378.13 +/- 41.68 fmol/g) than in rats that had received either the low-sodium diet (137.30 +/- 26.11 fmol/g; p < 0.0005) or the high-sodium diet (182.64 +/- 28.63 fmol/g; p < 0.005).
    1 context sentence
    Summary · context
    Male Sprague-Dawley rats, eight in each group, were placed on low-sodium, normal-sodium, or high-sodium diets and distilled drinking water ad libitum for 7 days.

    This result measures the body's own Vasoactive intestinal peptide (VIP, aviptadil). Nobody was given the peptide. It is not evidence about taking it.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    12 Oct 2026, 12:58 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 12:41 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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