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Study · Animal study (in vivo) · mouse and rat · 1995

2 results

GH-deficient dw/dw rats and lit/lit mice show increased Fos expression in the hypothalamic arcuate nucleus following systemic injection of GH-releasing peptide-6.

Dickson SL, Doutrelant-Viltart O, Leng G

The Journal of endocrinology1 Sept 1995Cited by 27 (Europe PMC)

Summary

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Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

2 results from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Mechanism

    In GH-deficient dw/dw rats, peripheral GHRP‑6 induced Fos expression in the arcuate nucleus.

    In plain wordsIn growth hormone deficient rats, peripheral GHRP‑6 induced Fos expression in the arcuate nucleus.

    Peptide
    GHRP-6
    Outcome
    IncreaseArcuate Fos expression
    Study

    ratn: not reported in source

    GH-deficient dw/dw rats
    Outcome group
    Receptor activity and mechanism · Endocrine and hormones
    Studied dose
    Dose not stated · peripheral administrationAs given in this study (rat).

    Source sentences

    Summary
    First, we demonstrated that peripherally administered GHRP-6 induces Fos expression in the arcuate nucleus of GH-deficient animals (dw/dw rats and lit/lit mice).
  2. 02AnimalAnimal study (in vivo)Mechanism

    In GH-deficient lit/lit mice, peripheral GHRP‑6 induced Fos expression in the arcuate nucleus.

    In plain wordsIn growth hormone deficient mice, peripheral GHRP‑6 induced Fos expression in the arcuate nucleus.

    Peptide
    GHRP-6
    Outcome
    IncreaseArcuate Fos expression
    Study

    mousen: not reported in source

    GH-deficient lit/lit mice
    Outcome group
    Receptor activity and mechanism · Endocrine and hormones
    Studied dose
    Dose not stated · peripheral administrationAs given in this study (mouse).

    Source sentences

    Summary
    First, we demonstrated that peripherally administered GHRP-6 induces Fos expression in the arcuate nucleus of GH-deficient animals (dw/dw rats and lit/lit mice).

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    21 Oct 2026, 15:58 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 03:13 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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