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Study · Measured the body's own peptide · 1995

3 results

Human gastrin and vasoactive intestinal polypeptide responses to endurance running in relation to training status and fluid ingested.

MacLaren DP, Raine NM, O'Connor AM, Buchanan KD

Clinical science (London, England : 1979)1 Aug 1995Cited by 11 (Europe PMC)

PMID7554754 (opens in a new tab)DOI10.1042/cs0890137 (opens in a new tab)PepBankPUB-07554754
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study3

No result from this study comes from a test of the peptide.

Natural levels measured3

These results measure the body's own peptide. Nobody was given the peptide. They are not evidence about taking it. They are left out of key results, evidence counts and charts.

  1. 01HumanEndogenous levelOther designOther

    In six endurance runners and six hockey players, plasma VIP rose significantly above resting levels during 90 min of treadmill running, with and without fluid ingestion.

    In plain wordsIn runners and hockey players, the body's own VIP rose during a 90-minute treadmill run.

    Peptide
    Vasoactive intestinal peptide (VIP, aviptadil)
    Outcome
    IncreasePlasma VIP response to treadmill running
    Study

    n = 12

    Comparator
    Resting values
    Outcome group
    Endogenous peptide levels · Gastrointestinal

    Source sentences

    Summary
    Plasma vasoactive intestinal polypeptide levels increased significantly beyond resting levels for both groups during trial A (endurance runners, 76.1 +/- 53.7 ng/l; hockey players 155.6 +/- 41.9 ng/l) and trial B (endurance runners 47.5 +/- 21.3 ng/l; hockey players 132.9 +/- 43.9 ng/l).
    1 context sentence
    Summary · context
    Plasma concentrations of gastrin, glucose, vasoactive intestinal polypeptide and non-esterified fatty acid were analysed in six male endurance runners and six male hockey players before, during and 15 min after 90 min treadmill running at 65% maximum oxygen uptake under two conditions: no fluid inge…

    This result measures the body's own Vasoactive intestinal peptide (VIP, aviptadil). Nobody was given the peptide. It is not evidence about taking it.

  2. 02HumanEndogenous levelOther designOther

    The plasma VIP response to running was significantly smaller with 8% maltodextrin ingestion than with no fluid.

    In plain wordsNatural VIP levels rose less during running when the runners drank a sugar solution than when they drank nothing.

    Peptide
    Vasoactive intestinal peptide (VIP, aviptadil)
    Outcome
    DecreasePlasma VIP response with fluid ingestion versus no fluid
    Study

    n = 12

    Comparator
    No fluid ingestion (trial A)
    Outcome group
    Endogenous peptide levels · Gastrointestinal

    Source sentences

    Summary
    The vasoactive intestinal polypeptide response to trial B was significantly attenuated compared with trial A
    1 context sentence
    Summary · context
    Plasma concentrations of gastrin, glucose, vasoactive intestinal polypeptide and non-esterified fatty acid were analysed in six male endurance runners and six male hockey players before, during and 15 min after 90 min treadmill running at 65% maximum oxygen uptake under two conditions: no fluid inge…

    This result measures the body's own Vasoactive intestinal peptide (VIP, aviptadil). Nobody was given the peptide. It is not evidence about taking it.

  3. 03HumanEndogenous levelOther designOther

    After both running trials, hockey players had significantly higher plasma VIP than endurance runners.

    In plain wordsAfter running, hockey players had higher natural VIP levels in blood than endurance runners.

    Peptide
    Vasoactive intestinal peptide (VIP, aviptadil)
    Outcome
    IncreasePlasma VIP in hockey players versus endurance runners
    Study

    n = 12

    Comparator
    Endurance runners
    Outcome group
    Endogenous peptide levels · Gastrointestinal

    Source sentences

    Summary
    hockey players produced significantly elevated concentrations of plasma vasoactive intestinal polypeptide after both trials compared with endurance runners.
    1 context sentence
    Summary · context
    Plasma concentrations of gastrin, glucose, vasoactive intestinal polypeptide and non-esterified fatty acid were analysed in six male endurance runners and six male hockey players before, during and 15 min after 90 min treadmill running at 65% maximum oxygen uptake under two conditions: no fluid inge…

    This result measures the body's own Vasoactive intestinal peptide (VIP, aviptadil). Nobody was given the peptide. It is not evidence about taking it.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    9 Oct 2026, 19:08 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 12:41 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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