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Study · Measured the body's own peptide · 1980

2 results

Vasoactive intestinal peptide-associated inhibition of stimulated gastric secretion. II. Inhibition of pentagastrin-stimulated gastric secretion.

Escourrou J, Ebeid AM, Fischer JE

American journal of surgery1 Jun 1980Cited by 4 (Europe PMC)

PMID7386737 (opens in a new tab)DOI10.1016/0002-9610(80)90390-6 (opens in a new tab)PepBankPUB-07386737
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

No result from this study comes from a test of the peptide.

Natural levels measured2

These results measure the body's own peptide. Nobody was given the peptide. They are not evidence about taking it. They are left out of key results, evidence counts and charts.

  1. 01AnimalEndogenous levelAnimal study (in vivo)Other

    In dogs, pentagastrin significantly increased plasma levels of the body's own VIP.

    In plain wordsIn dogs, pentagastrin raised the body's own VIP levels in blood.

    Peptide
    Vasoactive intestinal peptide (VIP, aviptadil)
    Outcome
    IncreasePlasma VIP after pentagastrin
    Study

    dogn: not reported in source

    awake dogs with Heidenhain pouches, pentagastrin-stimulated secretion
    Outcome group
    Gastrointestinal protection · Gastrointestinal

    Source sentences

    Summary
    Plasma vasoactive intestinal peptide is significantly increased by pentagastrin, and this release is enhanced by intraduodenal hydrochloric acid.
    2 context sentences
    Summary · context
    The possible role of vasoactive intestinal peptide as an inhibitor of stimulated gastric secretion was investigated.
    Summary · context
    Awake dogs with Heidenhain pouches were stimulated with pentagastrin alone and in combination with intraduodenal instillation of various potential inhibitors of gastrointestinal secretion including isotonic phenylalanine, 3 percent hypertonic saline solution and 0.16 normal hydrochloric acid.

    This result measures the body's own Vasoactive intestinal peptide (VIP, aviptadil). Nobody was given the peptide. It is not evidence about taking it.

  2. 02AnimalEndogenous levelAnimal study (in vivo)Other

    In dogs, intraduodenal hydrochloric acid enhanced the pentagastrin-induced rise in plasma levels of the body's own VIP.

    In plain wordsIn dogs, putting acid into the gut raised the body's own VIP in blood further than pentagastrin alone.

    Peptide
    Vasoactive intestinal peptide (VIP, aviptadil)
    Outcome
    IncreasePlasma VIP release with intraduodenal hydrochloric acid
    Study

    dogn: not reported in source

    awake dogs with Heidenhain pouches, pentagastrin-stimulated secretion
    Outcome group
    Gastrointestinal protection · Gastrointestinal

    Source sentences

    Summary
    this release is enhanced by intraduodenal hydrochloric acid.
    2 context sentences
    Summary · context
    The possible role of vasoactive intestinal peptide as an inhibitor of stimulated gastric secretion was investigated.
    Summary · context
    Awake dogs with Heidenhain pouches were stimulated with pentagastrin alone and in combination with intraduodenal instillation of various potential inhibitors of gastrointestinal secretion including isotonic phenylalanine, 3 percent hypertonic saline solution and 0.16 normal hydrochloric acid.

    This result measures the body's own Vasoactive intestinal peptide (VIP, aviptadil). Nobody was given the peptide. It is not evidence about taking it.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    12 Oct 2026, 12:58 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 12:41 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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