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Study · Animal study (in vivo) · mouse · 1981

6 results

Influence of serum thymic factor (FTS) on radiation-induced leukaemogenesis in thymectomized AKR mice.

Legrand E, Daculsi R, Bach JF, Duplan JF

International journal of cancer1 Jul 1981Cited by 5 (Europe PMC)

PMID7198101 (opens in a new tab)DOI10.1002/ijc.2910280111 (opens in a new tab)PepBankPUB-07198101
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study6

6 results from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Safety outcome

    In thymectomized AKR mice, FTS did not alter overall leukemia frequency after irradiation.

    In plain wordsIn thymectomized AKR mice, FTS did not change the overall frequency of leukemia after irradiation.

    Peptide
    Thymulin (serum thymic factor)
    Outcome
    No significant changeOverall leukemia frequency
    Study

    mousen: not reported in source

    thymectomized irradiated AKR mice
    Outcome group
    Tumor growth · Cancer
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Although FTS did not modify the overall frequency of leukaemias, it increased significantly the incidence of the "early" null ones.
    1 context sentence
    Summary · context
    The influence of serum thymic factor (FTS) on extrathymic leukaemogenesis induced in thymectomized AKR mice by fractionated sub-lethal irradiation was studied.
  2. 02AnimalAnimal study (in vivo)Safety outcome

    In thymectomized AKR mice, FTS significantly increased early null leukemia incidence after irradiation.

    In plain wordsIn thymectomized AKR mice, FTS significantly increased early null leukemia after irradiation.

    Peptide
    Thymulin (serum thymic factor)
    Outcome
    IncreaseEarly null leukemia incidence
    Study

    mousen: not reported in source

    thymectomized irradiated AKR mice
    Outcome group
    Tumor growth · Cancer
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Although FTS did not modify the overall frequency of leukaemias, it increased significantly the incidence of the "early" null ones.
    1 context sentence
    Summary · context
    The influence of serum thymic factor (FTS) on extrathymic leukaemogenesis induced in thymectomized AKR mice by fractionated sub-lethal irradiation was studied.
  3. 03AnimalAnimal study (in vivo)Safety outcome

    In thymectomized AKR mice, FTS did not affect late null leukemia frequency.

    In plain wordsIn thymectomized AKR mice, FTS did not change late null leukemia frequency.

    Peptide
    Thymulin (serum thymic factor)
    Outcome
    No significant changeLate null leukemia frequency
    Study

    mousen: not reported in source

    thymectomized irradiated AKR mice
    Outcome group
    Tumor growth · Cancer
    Studied dose
    Dose not stated

    Source sentences

    Summary
    It had no effect on the frequency or the latency of late null and B leukaemias.
    1 context sentence
    Summary · context
    The influence of serum thymic factor (FTS) on extrathymic leukaemogenesis induced in thymectomized AKR mice by fractionated sub-lethal irradiation was studied.
  4. 04AnimalAnimal study (in vivo)Safety outcome

    In thymectomized AKR mice, FTS did not affect late null leukemia latency.

    In plain wordsIn thymectomized AKR mice, FTS did not change the time to late null leukemia.

    Peptide
    Thymulin (serum thymic factor)
    Outcome
    No significant changeLate null leukemia latency
    Study

    mousen: not reported in source

    thymectomized irradiated AKR mice
    Outcome group
    Tumor growth · Cancer
    Studied dose
    Dose not stated

    Source sentences

    Summary
    It had no effect on the frequency or the latency of late null and B leukaemias.
    1 context sentence
    Summary · context
    The influence of serum thymic factor (FTS) on extrathymic leukaemogenesis induced in thymectomized AKR mice by fractionated sub-lethal irradiation was studied.
  5. 05AnimalAnimal study (in vivo)Safety outcome

    In thymectomized AKR mice, FTS did not affect B leukemia frequency.

    In plain wordsIn thymectomized AKR mice, FTS did not change B leukemia frequency.

    Peptide
    Thymulin (serum thymic factor)
    Outcome
    No significant changeB leukemia frequency
    Study

    mousen: not reported in source

    thymectomized irradiated AKR mice
    Outcome group
    Tumor growth · Cancer
    Studied dose
    Dose not stated

    Source sentences

    Summary
    It had no effect on the frequency or the latency of late null and B leukaemias.
    1 context sentence
    Summary · context
    The influence of serum thymic factor (FTS) on extrathymic leukaemogenesis induced in thymectomized AKR mice by fractionated sub-lethal irradiation was studied.
  6. 06AnimalAnimal study (in vivo)Safety outcome

    In thymectomized AKR mice, FTS did not affect B leukemia latency.

    In plain wordsIn thymectomized AKR mice, FTS did not change the time to B leukemia.

    Peptide
    Thymulin (serum thymic factor)
    Outcome
    No significant changeB leukemia latency
    Study

    mousen: not reported in source

    thymectomized irradiated AKR mice
    Outcome group
    Tumor growth · Cancer
    Studied dose
    Dose not stated

    Source sentences

    Summary
    It had no effect on the frequency or the latency of late null and B leukaemias.
    1 context sentence
    Summary · context
    The influence of serum thymic factor (FTS) on extrathymic leukaemogenesis induced in thymectomized AKR mice by fractionated sub-lethal irradiation was studied.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    21 Oct 2026, 15:58 UTC

    Study results updated

  2. Version 1

    21 Oct 2026, 12:50 UTC

    First added · source update from Europe PMC

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