In spleen cells from neonatally thymectomized mice, synthetic thymosin alpha‑1 was inactive in the [3H]-thymidine incorporation assay of lymphocyte proliferation.
In plain wordsIn lab tests, synthetic thymosin alpha‑1 did not stimulate mouse spleen cell growth in this assay.
- Peptide
- Thymosin alpha-1
- Outcome
- No significant changeLymphocyte proliferation ([3H]-thymidine incorporation)
- Study
mousen: not reported in source
Spleen cells from neonatally thymectomized mice, [3H]-thymidine incorporation assay- Outcome group
- Immune response · Immune and inflammation
- Studied dose
- Dose not stated
Source sentences
Calf thymus outer fraction ("CTO") showed activity, but Fraction 5, synthetic thymosin alpha 1, [G1n1]-FTS, and glutathione, were inactive in this assay.
1 context sentence(design, population, supporting numbers)
The assay uses spleen cells from neonatally thymectomized mice as tissue relevant to immunoregulation.