In rats with pancreatic fistulae, dermorphin almost completely inhibited 2DG-stimulated pancreatic secretion, irrespective of gastric fistula status.
In plain wordsIn rats, dermorphin almost completely blocked stimulated pancreatic secretion, both with and without gastric fistulae.
- Peptide
- Dermorphin
- Outcome
- Decrease2DG-stimulated pancreatic secretion
- Study
ratn: not reported in source
conscious rats with pancreatic fistulae, with or without gastric fistulae- Outcome group
- Gastrointestinal function · Gastrointestinal
- Studied dose
- Dose not stated
Source sentences
Dermorphin almost completely inhibited the stimulant effect of 2DG, independently by different experimental conditions.
2 context sentences(design, population, supporting numbers)
The influence of the opioid peptide dermorphin on 2DG-stimulated pancreatic secretion of the rat was studied.
Experiments were performed in conscious rats with pancreatic fistulae (8 animals), or with pancreatic and gastric fistulae (8 rats) to allow diversion of gastric juice.