Immunohistochemical localization of vasoactive intestinal polypeptide (VIP)-containing neurons in the hypothalamus of the Japanese quail, Coturnix coturnix.

Yamada S, Mikami S, Yanaihara N

Cell and tissue research1 Jan 1982Cited by 47 (Europe PMC)

PMID7127414DOI10.1007/bf00217078PepBankPUB-07127414

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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study7

No result from this study comes from a test of the peptide.

Natural levels measured7

These results measure the body's own peptide. Nobody was given the peptide. They are not evidence about taking it. They are left out of key results, evidence counts and charts.

01AnimalEndogenous levelAnimal study (in vivo)Other
In the Japanese quail hypothalamus, VIP-immunoreactive perikarya were numerous in the caudal nucleus infundibularis and nucleus mamillaris lateralis and sparse in the preoptic area, nucleus supraopticus and nucleus paraventricularis.
In plain wordsIn quail, cells containing the body's own VIP were common in some hypothalamus areas and rare in others.
Peptide
Vasoactive intestinal peptide (VIP, aviptadil)
Outcome
Not applicableDistribution of VIP-immunoreactive perikarya in the hypothalamus
Study
Japanese quailn: not reported in source
Outcome group
Endogenous peptide levels · Nervous system and cognition
Source sentences
Summary
Numerous VIP-immunoreactive perikarya are distributed in the caudal portion of the nucleus infundibularis (n. tuberis) and nucleus mamillaris lateralis, and sparse in the preoptic area, nucleus supraopticus and nucleus paraventricularis.
1 context sentence(design, population, supporting numbers)
Summary · context
The localization of vasoactive intestinal polypeptide (VIP) in the hypothalamus of the quail has been studied by means of light- and electron-microscopic immunohistochemistry.
This result measures the body's own Vasoactive intestinal peptide (VIP, aviptadil). Nobody was given the peptide. It is not evidence about taking it.
Report a problemFND-0712741401
02AnimalEndogenous levelAnimal study (in vivo)Other
In the quail, dense VIP-immunoreactive fibres were present in the external layer of the median eminence, in close contact with the primary portal capillaries.
In plain wordsIn quail, dense nerve fibres containing the body's own VIP lay in the median eminence close to the small blood vessels there.
Peptide
Vasoactive intestinal peptide (VIP, aviptadil)
Outcome
Not applicableVIP-immunoreactive fibres in the median eminence
Study
Japanese quailn: not reported in source
Outcome group
Endogenous peptide levels · Nervous system and cognition
Source sentences
Summary
Dense localization of immunoreactive-VIP fibers is observed in the external layer of the median eminence, in close contact with the primary portal capillaries.
1 context sentence(design, population, supporting numbers)
Summary · context
The localization of vasoactive intestinal polypeptide (VIP) in the hypothalamus of the quail has been studied by means of light- and electron-microscopic immunohistochemistry.
This result measures the body's own Vasoactive intestinal peptide (VIP, aviptadil). Nobody was given the peptide. It is not evidence about taking it.
Report a problemFND-0712741402
03AnimalEndogenous levelAnimal study (in vivo)Other
In the quail, the main origin of the VIP fibre terminals was the VIP-immunoreactive perikarya of the nucleus infundibularis, which apparently form a tuberohypophysial tract.
In plain wordsIn quail, most nerve endings with the body's own VIP in the median eminence came from cells in the nucleus infundibularis.
Peptide
Vasoactive intestinal peptide (VIP, aviptadil)
Outcome
Not applicableOrigin of VIP fibre terminals in the median eminence
Study
Japanese quailn: not reported in source
Outcome group
Endogenous peptide levels · Nervous system and cognition
Source sentences
Summary
The main origins of these fiber terminals are VIP-immunoreactive perikarya of the nucleus infundibularis.
2 context sentences(design, population, supporting numbers)
Summary · context
They are CSF-contacting neurons and apparently constitute the tuberohypophysial tract that links the third ventricle and the hypophysial portal circulation.
Summary · context
The localization of vasoactive intestinal polypeptide (VIP) in the hypothalamus of the quail has been studied by means of light- and electron-microscopic immunohistochemistry.
This result measures the body's own Vasoactive intestinal peptide (VIP, aviptadil). Nobody was given the peptide. It is not evidence about taking it.
Report a problemFND-0712741403
04AnimalEndogenous levelAnimal study (in vivo)Other
In the quail, VIP-reactive neurons in the nucleus mamillaris lateralis projected axons to the external layer of the median eminence, forming the posterior bundle of the tuberohypophysial tract.
In plain wordsIn quail, cells containing the body's own VIP in the nucleus mamillaris lateralis sent fibres to the median eminence.
Peptide
Vasoactive intestinal peptide (VIP, aviptadil)
Outcome
Not applicableVIP-reactive projections from nucleus mamillaris lateralis
Study
Japanese quailn: not reported in source
Outcome group
Endogenous peptide levels · Nervous system and cognition
Source sentences
Summary
VIP-reactive neurons in the nucleus mamillaris lateralis also project axons to the external layer of the median eminence, constituting the posterior bundle of the tuberohypophysial tract.
1 context sentence(design, population, supporting numbers)
Summary · context
The localization of vasoactive intestinal polypeptide (VIP) in the hypothalamus of the quail has been studied by means of light- and electron-microscopic immunohistochemistry.
This result measures the body's own Vasoactive intestinal peptide (VIP, aviptadil). Nobody was given the peptide. It is not evidence about taking it.
Report a problemFND-0712741404
05AnimalEndogenous levelAnimal study (in vivo)Other
In the quail, numerous VIP-immunoreactive perikarya occurred in the nucleus accumbens/pars posterior close to the lateral ventricle.
In plain wordsIn quail, many cells containing the body's own VIP were found in the nucleus accumbens near the lateral ventricle.
Peptide
Vasoactive intestinal peptide (VIP, aviptadil)
Outcome
Not applicableVIP-immunoreactive perikarya in nucleus accumbens/pars posterior
Study
Japanese quailn: not reported in source
Outcome group
Endogenous peptide levels · Nervous system and cognition
Source sentences
Summary
Numerous VIP-immunoreactive perikarya occur also in the nucleus accumbens/pars posterior close to the lateral ventricle.
1 context sentence(design, population, supporting numbers)
Summary · context
The localization of vasoactive intestinal polypeptide (VIP) in the hypothalamus of the quail has been studied by means of light- and electron-microscopic immunohistochemistry.
This result measures the body's own Vasoactive intestinal peptide (VIP, aviptadil). Nobody was given the peptide. It is not evidence about taking it.
Report a problemFND-0712741405
06AnimalEndogenous levelAnimal study (in vivo)Other
In the quail, VIP-reactive fibres were moderately distributed in the area ventralis and area septalis.
In plain wordsIn quail, a moderate number of nerve fibres with the body's own VIP lay in the area ventralis and area septalis.
Peptide
Vasoactive intestinal peptide (VIP, aviptadil)
Outcome
Not applicableVIP-reactive fibres in area ventralis and area septalis
Study
Japanese quailn: not reported in source
Outcome group
Endogenous peptide levels · Nervous system and cognition
Source sentences
Summary
There are moderate distributions of VIP-reactive fibers in the area ventralis and in the area septalis.
1 context sentence(design, population, supporting numbers)
Summary · context
The localization of vasoactive intestinal polypeptide (VIP) in the hypothalamus of the quail has been studied by means of light- and electron-microscopic immunohistochemistry.
This result measures the body's own Vasoactive intestinal peptide (VIP, aviptadil). Nobody was given the peptide. It is not evidence about taking it.
Report a problemFND-0712741406
07AnimalEndogenous levelAnimal study (in vivo)Other
In the quail median eminence, VIP immunoreactivity was found in elementary granules of 75-115 nm diameter within nerve fibres.
In plain wordsIn quail, the body's own VIP sat in small granules inside nerve fibres of the median eminence.
Peptide
Vasoactive intestinal peptide (VIP, aviptadil)
Outcome
Not applicableUltrastructural location of VIP in median eminence fibres
Study
Japanese quailn: not reported in source
Outcome group
Endogenous peptide levels · Nervous system and cognition
Measurements
Granule diameter
75 to 115 nm
VIP-containing elementary granules in median eminence nerve fibres
Source sentences
Summary
Ultrastructurally, the immunoreactive products against VIP are found in the elementary granules, 75-115 nm in diameter, within the nerve fibers in the median eminence.
1 context sentence(design, population, supporting numbers)
Summary · context
The localization of vasoactive intestinal polypeptide (VIP) in the hypothalamus of the quail has been studied by means of light- and electron-microscopic immunohistochemistry.
This result measures the body's own Vasoactive intestinal peptide (VIP, aviptadil). Nobody was given the peptide. It is not evidence about taking it.
Report a problemFND-0712741407

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Version 2Current
12 Oct 2026, 12:58 UTC
Study results updated
Version 1
9 Oct 2026, 12:41 UTC
First added · source update from Europe PMC

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