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Study · Measured the body's own peptide · 1982

3 results

Immunochemical studies on thymosin: radioimmunoassay of thymosin alpha 1.

McClure JE, Lameris N, Wara DW, Goldstein AL

Journal of immunology (Baltimore, Md. : 1950)1 Jan 1982Cited by 81 (Europe PMC)

PMID7054279 (opens in a new tab)DOI10.4049/jimmunol.128.1.368 (opens in a new tab)PepBankPUB-07054279
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study3

No result from this study comes from a test of the peptide.

Natural levels measured2

These results measure the body's own peptide. Nobody was given the peptide. They are not evidence about taking it. They are left out of key results, evidence counts and charts.

  1. 01HumanEndogenous levelObservational studyOther

    The concentration of the body's own thymosin alpha‑1 in human blood was highest in utero, fell sharply after birth and stayed fairly constant over the first 15 years of life.

    In plain wordsIn people, the body's own thymosin alpha‑1 level in blood is highest before birth and drops sharply after birth.

    Peptide
    Thymosin alpha-1
    Outcome
    DecreaseBlood thymosin alpha 1 concentration by age
    Study

    n: not reported in source

    Outcome group
    Aging markers · Immune and inflammation

    Source sentences

    Summary
    The concentration of thymosin alpha 1 in the blood is highest in utero, decreases sharply after birth, and appears to remain fairly constant during the first 15 yr of life.
    1 context sentence
    Summary · context
    A sensitive and specific radioimmunoassay (RIA) has been developed to measure thymosin alpha 1 in human blood and tissue extracts.

    This result measures the body's own Thymosin alpha-1. Nobody was given the peptide. It is not evidence about taking it.

  2. 02HumanEndogenous levelObservational studyOther

    Maternal blood levels of thymosin alpha‑1 appeared to be above normal during pregnancy.

    In plain wordsIn pregnant women, the body's own thymosin alpha‑1 level in blood seemed higher than normal.

    Peptide
    Thymosin alpha-1
    Outcome
    IncreaseMaternal blood thymosin alpha 1 during pregnancy
    Study

    n: not reported in source

    Outcome group
    Sex hormones and fertility · Reproductive and sexual health

    Source sentences

    Summary
    Maternal blood levels of thymosin alpha 1 appear to be above normal during pregnancy.
    1 context sentence
    Summary · context
    A sensitive and specific radioimmunoassay (RIA) has been developed to measure thymosin alpha 1 in human blood and tissue extracts.

    This result measures the body's own Thymosin alpha-1. Nobody was given the peptide. It is not evidence about taking it.

Studies that did not test the peptide alone1

In this study, Thymosin alpha-1 was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking Thymosin alpha-1.

  1. 03LabNot a test of Thymosin alpha-1 aloneIn vitro (cell-free)Other

    A radioimmunoassay detected thymosin alpha‑1 in serum or plasma down to 40 pg without significant cross-reaction with other putative thymic hormones or blood proteins.

    In plain wordsIn lab tests, a new blood test could detect very small amounts of thymosin alpha‑1.

    Peptide
    Thymosin alpha-1
    Outcome
    Not applicableRadioimmunoassay detection limit for thymosin alpha 1
    Study

    n: not reported in source

    Radioimmunoassay
    Outcome group
    Pharmacokinetics · Pharmacology

    Measurements

    detection limit
    40 pg
    serum/plasma

    Source sentences

    Summary
    The RIA is capable of detecting as small an amount as 40 pg thymosin alpha 1 in serum/plasma and does not significantly cross-react with other putative thymic hormones or other purified blood proteins that have been assayed.

    In this study, Thymosin alpha-1 was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Thymosin alpha-1.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 3Current

    10 Oct 2026, 08:55 UTC

    Study results updated

  2. Version 2

    9 Oct 2026, 03:03 UTC

    Study data updated · source update from Europe PMC

  3. Version 1

    9 Oct 2026, 03:02 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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