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Study · Measured the body's own peptide · 1982

3 results

Age-related changes in localization of thymosin in the human thymus.

Hirokawa K, McClure JE, Goldstein AL

Thymus1 Jan 1982Cited by 64 (Europe PMC)

PMID7036424 (opens in a new tab)PepBankPUB-07036424
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study3

No result from this study comes from a test of the peptide.

Natural levels measured3

These results measure the body's own peptide. Nobody was given the peptide. They are not evidence about taking it. They are left out of key results, evidence counts and charts.

  1. 01HumanEndogenous levelObservational studyOther

    In human thymus glands, the body's own thymosin alpha‑1 was detected specifically in thymic epithelial cells of the medulla and in cells covering the cortical surface.

    In plain wordsIn human thymus glands, the body's own thymosin alpha‑1 was found in epithelial cells of the medulla and on the cortical surface.

    Peptide
    Thymosin alpha-1
    Outcome
    Not applicableThymosin alpha 1 localization in human thymus
    Study

    n: not reported in source

    Outcome group
    Immune response · Immune and inflammation

    Source sentences

    Summary
    Thymosin alpha 1 was detected specifically in thymic epithelial cells of the medulla and in cells covering the cortical surface.
    1 context sentence
    Summary · context
    Using an indirect fluorescent antibody technique, localization of thymosin alpha 1, thymosin beta 3 and thymosin fraction 6 was studied in human thymus glands ranging in age from newborn to 62 yr old.

    This result measures the body's own Thymosin alpha-1. Nobody was given the peptide. It is not evidence about taking it.

  2. 02HumanEndogenous levelObservational studyOther

    In human thymus, medullary epithelial cells positive for thymosin alpha‑1 decreased in number progressively with age, beginning at around 13 years.

    In plain wordsIn human thymus, the number of cells with the body's own thymosin alpha‑1 in the medulla fell with age from about 13 years.

    Peptide
    Thymosin alpha-1
    Outcome
    DecreaseMedullary epithelial cells positive for thymosin alpha 1 by age
    Study

    n: not reported in source

    Outcome group
    Aging markers · Immune and inflammation

    Source sentences

    Summary
    Epithelial cells in the medulla, which were positive for thymosin alpha 1, decreased in number progressively with age, beginning at around 13 yr of age.
    1 context sentence
    Summary · context
    Using an indirect fluorescent antibody technique, localization of thymosin alpha 1, thymosin beta 3 and thymosin fraction 6 was studied in human thymus glands ranging in age from newborn to 62 yr old.

    This result measures the body's own Thymosin alpha-1. Nobody was given the peptide. It is not evidence about taking it.

  3. 03HumanEndogenous levelObservational studyOther

    In human thymus, cortical-surface epithelial cells positive for thymosin alpha‑1 were present at all ages, although their absolute number decreased.

    In plain wordsIn human thymus, cells on the surface carrying the body's own thymosin alpha‑1 were seen at all ages, though fewer with age.

    Peptide
    Thymosin alpha-1
    Outcome
    DecreaseCortical surface cells positive for thymosin alpha 1 by age
    Study

    n: not reported in source

    Outcome group
    Aging markers · Immune and inflammation

    Source sentences

    Summary
    Epithelial cells positive for thymosin alpha 1 and covering the cortical surface were observed in thymus tissue from all ages, although the absolute number decreased.
    1 context sentence
    Summary · context
    Using an indirect fluorescent antibody technique, localization of thymosin alpha 1, thymosin beta 3 and thymosin fraction 6 was studied in human thymus glands ranging in age from newborn to 62 yr old.

    This result measures the body's own Thymosin alpha-1. Nobody was given the peptide. It is not evidence about taking it.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 3Current

    10 Oct 2026, 08:55 UTC

    Study results updated

  2. Version 2

    9 Oct 2026, 03:03 UTC

    Study data updated · source update from Europe PMC

  3. Version 1

    9 Oct 2026, 03:02 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

Publication types

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