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Study · In vitro (cells) · mouse · 1982

3 results

Development and continuous growth in culture of interleukin 2-producer lymphocytes from athymic nu/nu mice.

Palacios R, Fernandez C, Sideras P

European journal of immunology1 Sept 1982Cited by 14 (Europe PMC)

PMID6982822 (opens in a new tab)DOI10.1002/eji.1830120914 (opens in a new tab)PepBankPUB-06982822
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study3

3 results from studies that gave the peptide. No result from this study comes from people.

  1. 01LabIn vitro (cells)Mechanism

    In nude mouse splenocytes, FTS pretreatment followed by PMA stimulation produced IL 2, whereas FTS or mitogens alone did not.

    In plain wordsIn mouse cells, FTS followed by PMA produced IL 2, whereas FTS or mitogens alone did not.

    Peptide
    Thymulin (serum thymic factor)
    Outcome
    IncreaseIL 2 production after PMA stimulation
    Study

    mousen: not reported in source

    Splenocytes from athymic nu/nu mice
    Comparator
    PMA alone
    Outcome group
    Immune response · Immune and inflammation
    Studied dose
    Dose not stated · 3 or more daysAs given in this study (mouse).

    Source sentences

    Summary
    Splenocytes of nu/nu mice treated with serum thymic factor (FTS) for 3 or more days followed by stimulation with either phorbol myristate acetate (PMA) or concanavalin A (Con A) produced interleukin 2 (IL 2)
    1 context sentence
    Summary · context
    However, neither mitogens nor FTS alone could induce nude mice cells to product IL 2.
  2. 02LabIn vitro (cells)Mechanism

    In nude mouse splenocytes, FTS pretreatment followed by Con A stimulation produced IL 2, whereas FTS or mitogens alone did not.

    In plain wordsIn mouse cells, FTS followed by Con A produced IL 2, whereas FTS or mitogens alone did not.

    Peptide
    Thymulin (serum thymic factor)
    Outcome
    IncreaseIL 2 production after Con A stimulation
    Study

    mousen: not reported in source

    Splenocytes from athymic nu/nu mice
    Comparator
    Con A alone
    Outcome group
    Immune response · Immune and inflammation
    Studied dose
    Dose not stated · 3 or more daysAs given in this study (mouse).

    Source sentences

    Summary
    Splenocytes of nu/nu mice treated with serum thymic factor (FTS) for 3 or more days followed by stimulation with either phorbol myristate acetate (PMA) or concanavalin A (Con A) produced interleukin 2 (IL 2)
    1 context sentence
    Summary · context
    However, neither mitogens nor FTS alone could induce nude mice cells to product IL 2.
  3. 03LabIn vitro (cells)Mechanism

    In nude mouse splenocytes, FTS alone could not induce IL 2 production.

    In plain wordsIn mouse cells, FTS alone did not induce IL 2 production.

    Peptide
    Thymulin (serum thymic factor)
    Outcome
    No significant changeIL 2 induction with FTS alone
    Study

    mousen: not reported in source

    Splenocytes from athymic nu/nu mice
    Outcome group
    Immune response · Immune and inflammation
    Studied dose
    Dose not stated

    Source sentences

    Summary
    However, neither mitogens nor FTS alone could induce nude mice cells to product IL 2.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    21 Oct 2026, 15:58 UTC

    Study results updated

  2. Version 1

    21 Oct 2026, 12:50 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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