In human Tar lymphocytes, serum thymic factor enabled cytotoxicity against allogeneic targets, whereas cells without either stimulant showed little or no cytotoxicity.
In plain wordsIn human cells, FTS enabled killing of allogeneic target cells compared with little or no activity without either stimulant.
- Outcome
- IncreaseCytotoxicity against allogeneic target cells
- Study
humann: not reported in source
Autologous rosette-forming T lymphocytes- Comparator
- Absence of interleukin-2 or serum thymic factor
- Outcome group
- Immune response · Immune and inflammation
- Studied dose
- Dose not stated
Source sentences
In addition, we found that Tar lymphocytes were able to develop cytotoxicity against allogeneic and trinitrophenol (TNP)-conjugated autologous target cells in the presence of interleukin-2 (IL-2) or serum thymic factor.
2 context sentences(design, population, supporting numbers)
However, these cells showed little or nor cytotoxicity in the absence of interleukin-2 or serum thymic factor.
The autologous rosette-forming T cells (Tar cells) isolated by means of their ability to form rosettes with autologous erythrocytes were characterized by the use of OKT monoclonal anti-human T-cell subset antibodies and a monoclonal anti-HLA-DR antibody.