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Study · In vitro (cells) · 1982

1 result

Modulation of T leukaemic cell phenotype with phorbol ester.

Delia D, Greaves MF, Newman RA, Sutherland DR, Minowada J, Kung P, Goldstein G

International journal of cancer1 Jan 1982Cited by 73 (Europe PMC)

PMID6977500 (opens in a new tab)DOI10.1002/ijc.2910290106 (opens in a new tab)PepBankPUB-06977500
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study1

1 result from studies that gave the peptide. No result from this study comes from people.

  1. 01LabIn vitro (cells)Mechanism

    Human T leukaemic cell lines were unresponsive to FTS in tests of phenotypic maturation.

    In plain wordsIn human leukemia cells, FTS produced no reported phenotypic maturation response.

    Peptide
    Thymulin (serum thymic factor)
    Outcome
    No significant changePhenotypic maturation response
    Study

    humann: not reported in source

    Human T leukaemic cell lines
    Outcome group
    Receptor activity and mechanism · Cancer
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Seven cell lines underwent multiple phenotypic alterations in response to TPA but were unresponsive to synthetic thymic hormones (TP5, FTS) or to other compounds (e.g. DMSO, retinoic acid) which induce maturation in other types of leukaemia.
    1 context sentence
    Summary · context
    to monitor the induction of maturation in human thymic (T) leukaemic cell lines by phorbol ester (TPA).

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Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    21 Oct 2026, 15:58 UTC

    Study results updated

  2. Version 1

    21 Oct 2026, 12:50 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

Publication types

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