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Study · Measured the body's own peptide · 1982

4 results

[Level of delta sleep-inducing peptide (DSIP) in the brain of rats with different alcoholic motivation].

Burov IuV, Iukhananov RIu, Maĭskiĭ AI

Biulleten' eksperimental'noi biologii i meditsiny1 Sept 1982

PMID6897366 (opens in a new tab)PepBankPUB-06897366
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study4

No result from this study comes from a test of the peptide.

Natural levels measured4

These results measure the body's own peptide. Nobody was given the peptide. They are not evidence about taking it. They are left out of key results, evidence counts and charts.

  1. 01AnimalEndogenous levelAnimal study (in vivo)Other

    In rats, short-sleeping animals had lower DSIP content in intact brain homogenates, cortex of large hemispheres and striatum.

    In plain wordsIn rats that slept briefly after ethanol, the body's own DSIP level was lower in some brain parts.

    Peptide
    Delta sleep-inducing peptide (DSIP)
    Outcome
    DecreaseDSIP content in brain of short-sleeping rats
    Study

    ratn: not reported in source

    Outcome group
    Endogenous peptide levels · Nervous system and cognition

    Source sentences

    Summary
    The short-sleeping rats manifested a statistically significant lowering of the DSIP content in intact brain homogenates, in the cortex of large hemispheres and striatum.
    1 context sentence
    Summary · context
    Radioimmunoassay was used to measure the content of delta-sleep-inducing peptide (DSIP) in random-bred albino rats divided into groups according to the duration of ethanol anesthesia and the levels of 15% ethanol consumption under free-choice conditions.

    This result measures the body's own Delta sleep-inducing peptide (DSIP). Nobody was given the peptide. It is not evidence about taking it.

  2. 02AnimalEndogenous levelAnimal study (in vivo)Other

    In rats, thirty minutes after a single intraperitoneal ethanol injection of 1 g/kg, DSIP content rose in the medulla oblongata, thalamus and striatum.

    In plain wordsIn rats, a single ethanol injection raised the body's own DSIP level in some brain parts shortly after.

    Peptide
    Delta sleep-inducing peptide (DSIP)
    Outcome
    IncreaseDSIP content after single ethanol injection (1 g/kg)
    Study

    ratn: not reported in source

    Outcome group
    Endogenous peptide levels · Nervous system and cognition

    Source sentences

    Summary
    On the contrary, thirty minutes after a single intraperitoneal injection of ethanol in a dose of 1 g/kg the DSIP content in the medulla oblongata, thalamus and striatum was found to be increased.
    1 context sentence
    Summary · context
    Radioimmunoassay was used to measure the content of delta-sleep-inducing peptide (DSIP) in random-bred albino rats divided into groups according to the duration of ethanol anesthesia and the levels of 15% ethanol consumption under free-choice conditions.

    This result measures the body's own Delta sleep-inducing peptide (DSIP). Nobody was given the peptide. It is not evidence about taking it.

  3. 03AnimalEndogenous levelAnimal study (in vivo)Other

    In rats, higher ethanol doses of 2.5 and 4.5 g/kg were followed by a less significant increase in brain DSIP content.

    In plain wordsIn rats, higher ethanol doses raised the body's own DSIP level less than the lower dose did.

    Peptide
    Delta sleep-inducing peptide (DSIP)
    Outcome
    IncreaseDSIP content after higher ethanol doses (2.5 and 4.5 g/kg)
    Study

    ratn: not reported in source

    Outcome group
    Endogenous peptide levels · Nervous system and cognition

    Source sentences

    Summary
    The raising of the ethanol dose up to 2.5 and 4.5 g/kg was followed by a less significant increase in the neuropeptide content.
    1 context sentence
    Summary · context
    Radioimmunoassay was used to measure the content of delta-sleep-inducing peptide (DSIP) in random-bred albino rats divided into groups according to the duration of ethanol anesthesia and the levels of 15% ethanol consumption under free-choice conditions.

    This result measures the body's own Delta sleep-inducing peptide (DSIP). Nobody was given the peptide. It is not evidence about taking it.

  4. 04AnimalEndogenous levelAnimal study (in vivo)Other

    In rats, 12 months of chronic alcoholization under free-choice conditions reduced DSIP content in the medulla oblongata, thalamus and striatum.

    In plain wordsIn rats, long-term alcohol drinking lowered the body's own DSIP level in some brain parts.

    Peptide
    Delta sleep-inducing peptide (DSIP)
    Outcome
    DecreaseDSIP content after 12 months of chronic alcoholization
    Study

    ratn: not reported in source

    Outcome group
    Endogenous peptide levels · Nervous system and cognition

    Source sentences

    Summary
    Prolonged chronic alcoholization under free-choice conditions led after 12 months to the reduced DSIP content in the medulla oblongata, thalamus and striatum.
    1 context sentence
    Summary · context
    Radioimmunoassay was used to measure the content of delta-sleep-inducing peptide (DSIP) in random-bred albino rats divided into groups according to the duration of ethanol anesthesia and the levels of 15% ethanol consumption under free-choice conditions.

    This result measures the body's own Delta sleep-inducing peptide (DSIP). Nobody was given the peptide. It is not evidence about taking it.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    12 Oct 2026, 17:28 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 03:04 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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