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Study · Animal study (in vivo) · rabbit · 1982

3 results

[Action of the "delta-sleep peptide" on monoamine oxidase and acetylcholinesterase activity in subcellular fractions from different rabbit brain formations in vivo].

Dovedova EL, Ashmarin IP

Biulleten' eksperimental'noi biologii i meditsiny1 May 1982Cited by 1 (Europe PMC)

PMID6896465 (opens in a new tab)PepBankPUB-06896465
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study3

3 results from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Mechanism

    In rabbits, DSIP at 30 microgram/kg activated monoamine oxidase A in synaptosome subfractions and cellular mitochondria of the motor cortex, nucleus caudatus and thalamus.

    In plain wordsIn rabbits, DSIP raised the activity of the enzyme MAO-A in parts of the brain.

    Peptide
    Delta sleep-inducing peptide (DSIP)
    Outcome
    IncreaseMAO-A activity (substrate serotonin) in synaptosome subfractions and mitochondria
    Study

    rabbitn: not reported in source

    Outcome group
    Receptor activity and mechanism · Nervous system and cognition
    Studied dose
    30 microgram/kg bwAs given in this study (rabbit).

    Source sentences

    Summary
    Administration of delta-sleep-inducing peptide (DSIP) in vivo in a dose of 30 microgram/kg bw brings about MAO-A (substrate-serotonin) activation in synaptosome subfractions and cellular mitochondria from the brain structures (motor cortex, nucleus caudatus, thalamus).
    1 context sentence
    Title · context
    [Action of the "delta-sleep peptide" on monoamine oxidase and acetylcholinesterase activity in subcellular fractions from different rabbit brain formations in vivo].
  2. 02AnimalAnimal study (in vivo)Mechanism

    In rabbits, DSIP inhibited MAO-B activity only negligibly in subcellular fractions of the test brain structures.

    In plain wordsIn rabbits, DSIP barely changed the activity of the enzyme MAO-B in parts of the brain.

    Peptide
    Delta sleep-inducing peptide (DSIP)
    Outcome
    No significant changeMAO-B activity (substrate p-nitrophenylethylamine)
    Study

    rabbitn: not reported in source

    Outcome group
    Receptor activity and mechanism · Nervous system and cognition
    Studied dose
    30 microgram/kg bwAs given in this study (rabbit).

    Source sentences

    Summary
    Activity of MAO-B (substrate-p-nitrophenylethylamine) and acetylcholinesterase was inhibited negligibly
    1 context sentence
    Title · context
    [Action of the "delta-sleep peptide" on monoamine oxidase and acetylcholinesterase activity in subcellular fractions from different rabbit brain formations in vivo].
  3. 03AnimalAnimal study (in vivo)Mechanism

    In rabbits, DSIP inhibited acetylcholinesterase activity only negligibly in subcellular fractions of the test brain structures.

    In plain wordsIn rabbits, DSIP barely changed the activity of the enzyme acetylcholinesterase in parts of the brain.

    Peptide
    Delta sleep-inducing peptide (DSIP)
    Outcome
    No significant changeAcetylcholinesterase activity
    Study

    rabbitn: not reported in source

    Outcome group
    Receptor activity and mechanism · Nervous system and cognition
    Studied dose
    30 microgram/kg bwAs given in this study (rabbit).

    Source sentences

    Summary
    Activity of MAO-B (substrate-p-nitrophenylethylamine) and acetylcholinesterase was inhibited negligibly and specifically in subcellular fractions of the test brain structures.
    1 context sentence
    Title · context
    [Action of the "delta-sleep peptide" on monoamine oxidase and acetylcholinesterase activity in subcellular fractions from different rabbit brain formations in vivo].

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    12 Oct 2026, 17:28 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 03:04 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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