The C-terminal half of thymosin alpha‑1, residues 15-28, was synthesised with polymer-bound 1-hydroxybenzotriazole (PHBT) activation of each coupling step.
In plain wordsIn lab chemistry, the second half of thymosin alpha‑1 was made with a polymer-supported coupling method.
- Peptide
- Thymosin alpha-1
- Outcome
- Not applicableSynthesis of thymosin alpha 1 (15-28) with PHBT
- Study
n: not reported in source
Polymeric reagent peptide synthesis- Outcome group
- Analytical methods and detection · Pharmacology
Source sentences
This was demonstrated by the synthesis of thymosin alpha 1 (15-28)
1 context sentence(design, population, supporting numbers)
After appropriate deblocking of 2, segments 2 and 3 were coupled by the DCC-HOBT method, followed by complete deblocking and ion-exchange chromatographic purification, affording the C-terminal half of thymosin alpha 1, H-Asp-Leu-Lys-Glu-Lys-Lys-Glu-Val-Val-Glu-Glu-Ala-Glu-Asn-OH (1).
In this study, Thymosin alpha-1 was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Thymosin alpha-1.