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Study · Measured the body's own peptide · 1981

4 results

Immunohistochemistry of vasopressin, oxytocin and neurophysin in the hypothalamus and extrahypothalamic regions of the human and primate brain.

Sofroniew MV, Weindl A, Schrell U, Wetzstein R

Acta histochemica. Supplementband1 Jan 1981Cited by 54 (Europe PMC)

PMID6785843 (opens in a new tab)PepBankPUB-06785843
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study4

No result from this study comes from a test of the peptide.

Natural levels measured4

These results measure the body's own peptide. Nobody was given the peptide. They are not evidence about taking it. They are left out of key results, evidence counts and charts.

  1. 01LabEndogenous levelEx vivo tissueActivity measurement

    In human and primate brain tissue, magnocellular hypothalamic neurons stained positively for endogenous oxytocin.

    In plain wordsIn lab tests of human and primate tissue, magnocellular hypothalamic neurons showed a staining signal for the body's own oxytocin.

    Peptide
    Oxytocin
    Outcome
    Not applicableOxytocin staining in hypothalamic magnocellular neurons
    Study

    tree shrew, squirrel monkey, rhesus monkey and humann: not reported in source

    Human and primate brain and spinal-cord tissue
    Outcome group
    Receptor activity and mechanism · Nervous system and cognition

    Source sentences

    Summary
    Magnocellular neurons in the hypothalamus stained positively for vasopressin, oxytocin or neurophysin.
    1 context sentence
    Summary · context
    Vasopressin, oxytocin and neurophysin were localized in the brains and spinal cords of four primates (tree shrew, squirrel monkey, rhesus monkey and human) using antisera to these peptides and the unlabelled antibody-enzyme peroxidase antiperoxidase method.

    This result measures the body's own Oxytocin. Nobody was given the peptide. It is not evidence about taking it.

  2. 02LabEndogenous levelEx vivo tissueActivity measurement

    In human and primate brain tissue, parvocellular suprachiasmatic-nucleus neurons showed no positive staining signal for endogenous oxytocin.

    In plain wordsIn lab tests of human and primate tissue, these suprachiasmatic neurons showed no staining signal for the body's own oxytocin.

    Peptide
    Oxytocin
    Outcome
    Not applicableOxytocin staining in suprachiasmatic-nucleus parvocellular neurons
    Study

    tree shrew, squirrel monkey, rhesus monkey and humann: not reported in source

    Human and primate brain and spinal-cord tissue
    Outcome group
    Receptor activity and mechanism · Nervous system and cognition

    Source sentences

    Summary
    Parvocellular neurons of the suprachiasmatic nucleus (SCN) stained positively for vasopressin and neurophysin but not for oxytocin, in all four species.
    1 context sentence
    Summary · context
    Vasopressin, oxytocin and neurophysin were localized in the brains and spinal cords of four primates (tree shrew, squirrel monkey, rhesus monkey and human) using antisera to these peptides and the unlabelled antibody-enzyme peroxidase antiperoxidase method.

    This result measures the body's own Oxytocin. Nobody was given the peptide. It is not evidence about taking it.

  3. 03LabEndogenous levelEx vivo tissueActivity measurement

    In primate neural tissue, magnocellular oxytocin neurons projected to neurohypophysial capillaries and extrahypothalamic neural targets, although not all projections found in other primates could be confirmed in human autopsy tissue.

    In plain wordsIn lab tests of primate tissue, neurons with the body's own oxytocin projected to capillaries and targets, but not all were confirmed in human tissue.

    Peptide
    Oxytocin
    Outcome
    Not applicableOxytocin neuronal projections to neural targets
    Study

    tree shrew, squirrel monkey, rhesus monkey and humann: not reported in source

    Human and primate brain and spinal-cord tissue
    Outcome group
    Receptor activity and mechanism · Nervous system and cognition

    Source sentences

    Summary
    Magnocellular oxytocin, vasopressin and neurophysin neurons project to permeable capillaries in the neurohypophysis, as well as to various extrahypothalamic neural target areas including the central amygdala, nucleus of the solitary tract, dorsal motor nucleus of the vagus, lateral reticular nucleus…
    1 context sentence
    Summary · context
    (Due to the relatively poor tissue preservation in human autopsy specimens not all projections found in the other primates could be confirmed in humans.)

    This result measures the body's own Oxytocin. Nobody was given the peptide. It is not evidence about taking it.

  4. 04LabEndogenous levelEx vivo tissueActivity measurement

    In primate neural tissue, terminals of magnocellular oxytocin, vasopressin and neurophysin neurons contacted somata and dendrites in target areas.

    In plain wordsIn lab tests of primate tissue, terminals of neurons stained for the body's own oxytocin, vasopressin and neurophysin contacted cell bodies and dendrites.

    Peptide
    Oxytocin
    Outcome
    Not applicableOxytocin-neuron terminal contacts in neural targets
    Study

    tree shrew, squirrel monkey, rhesus monkey and humann: not reported in source

    Human and primate brain and spinal-cord tissue
    Outcome group
    Receptor activity and mechanism · Nervous system and cognition

    Source sentences

    Summary
    Magnocellular oxytocin, vasopressin and neurophysin neurons project to permeable capillaries in the neurohypophysis, as well as to various extrahypothalamic neural target areas
    1 context sentence
    Summary · context
    In target areas, terminals contact somata and dendrites.

    This result measures the body's own Oxytocin. Nobody was given the peptide. It is not evidence about taking it.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    11 Oct 2026, 20:03 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 02:53 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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