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Study · Animal study (in vivo) · rat · 1984

2 results

Effects of adrenalectomy, propranolol and methylatropine on the increase in heart rate induced by injection of dermorphin in the rat anterior hypothalamic nucleus.

Diz DI, Jacobowitz DM

Brain research1 Feb 1984Cited by 8 (Europe PMC)

PMID6704719 (opens in a new tab)DOI10.1016/0006-8993(84)91471-9 (opens in a new tab)PepBankPUB-06704719
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

2 results from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Activity measurement

    In halothane-anesthetized rats, anterior hypothalamic dermorphin increased heart rate by 17%.

    In plain wordsIn anesthetized rats, dermorphin in the anterior hypothalamus increased heart rate by 17%.

    Peptide
    Dermorphin
    Outcome
    IncreaseHeart rate
    Study

    ratn: not reported in source

    halothane-anesthetized rats
    Outcome group
    Heart function · Cardiovascular
    Studied dose
    40 pmol · anterior hypothalamic injectionAs given in this study (rat).

    Measurements

    Heart rate increase
    17%
    anterior hypothalamic dermorphin

    Source sentences

    Summary
    Anterior hypothalamic injections of 40 pmol dermorphin, a potent opiate receptor agonist, increased heart rate 17% and had no effect on blood pressure in halothane-anesthetized rats.
  2. 02AnimalAnimal study (in vivo)Activity measurement

    In halothane-anesthetized rats, anterior hypothalamic dermorphin had no effect on blood pressure.

    In plain wordsIn anesthetized rats, dermorphin in the anterior hypothalamus did not change blood pressure.

    Peptide
    Dermorphin
    Outcome
    No significant changeBlood pressure
    Study

    ratn: not reported in source

    halothane-anesthetized rats
    Outcome group
    Blood pressure · Cardiovascular
    Studied dose
    40 pmol · anterior hypothalamic injectionAs given in this study (rat).

    Source sentences

    Summary
    Anterior hypothalamic injections of 40 pmol dermorphin, a potent opiate receptor agonist, increased heart rate 17% and had no effect on blood pressure in halothane-anesthetized rats.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    27 Oct 2026, 18:20 UTC

    Study results updated

  2. Version 1

    27 Oct 2026, 16:32 UTC

    First added · source update from Europe PMC

Subjects

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Publication types

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