In adult thymectomized mice, in vivo thymosin alpha‑1 restored the lowered azathioprine sensitivity of spleen cells.
In plain wordsIn mice without a thymus, thymosin alpha‑1 restored a lowered immune cell function.
- Peptide
- Thymosin alpha-1
- Outcome
- IncreaseAzathioprine sensitivity of spleen cells
- Study
mousen: not reported in source
adult thymectomized mice- Outcome group
- Immune response · Immune and inflammation
- Studied dose
- Dose not stated
Source sentences
Thymosin alpha1 is able to restore the lowered levels of these T-dependent functions after in vivo administration.
1 context sentence(design, population, supporting numbers)
The effects of a synthetic thymosin alpha1 on the azathioprine-sensitivity of spleen cells and on the thymic-like activity of serum from adult thymectomized mice, were observed.