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Study · Animal study (in vivo) · rat · 1983

2 results

Increased sleep following intracerebroventricular injection of the delta sleep-inducing peptide in rats.

Ursin R, Larsen M

Neuroscience letters1 Sept 1983Cited by 46 (Europe PMC)

PMID6688864 (opens in a new tab)DOI10.1016/0304-3940(83)90293-8 (opens in a new tab)PepBankPUB-06688864
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

2 results from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Efficacy outcome

    In rats, intracerebroventricular DSIP at 7 nmol/kg increased total slow wave sleep by 20% compared with a baseline recording after sham injection.

    In plain wordsIn rats, DSIP injected into the brain ventricles raised slow wave sleep by 20% compared with the rats' own baseline.

    Peptide
    Delta sleep-inducing peptide (DSIP)
    Outcome
    IncreaseTotal slow wave sleep
    Study

    ratn: not reported in source

    rats, intracerebroventricular injection
    Comparator
    Baseline recording after sham injection
    Outcome group
    Sleep · Sleep
    Studied dose
    7 nmol/kg · intracerebroventricularAs given in this study (rat).

    Measurements

    Increase in total slow wave sleep
    20%
    DSIP-injected rats

    Source sentences

    Summary
    A significant, 20% increase in total slow wave sleep (and total sleep) was found in the DSIP-injected rats, compared to a baseline recording following a sham injection procedure.
    1 context sentence
    Summary · context
    Synthetic delta sleep-inducing peptide (DSIP) was injected intracerebroventricularly into rats in a dose of 7 nmol/kg.
  2. 02AnimalAnimal study (in vivo)Efficacy outcome

    In rats, intracerebroventricular DSIP at 7 nmol/kg increased total sleep by 20% compared with a baseline recording after sham injection.

    In plain wordsIn rats, DSIP injected into the brain ventricles raised total sleep by 20% compared with the rats' own baseline.

    Peptide
    Delta sleep-inducing peptide (DSIP)
    Outcome
    IncreaseTotal sleep
    Study

    ratn: not reported in source

    rats, intracerebroventricular injection
    Comparator
    Baseline recording after sham injection
    Outcome group
    Sleep · Sleep
    Studied dose
    7 nmol/kg · intracerebroventricularAs given in this study (rat).

    Measurements

    Increase in total sleep
    20%
    DSIP-injected rats

    Source sentences

    Summary
    A significant, 20% increase in total slow wave sleep (and total sleep) was found in the DSIP-injected rats, compared to a baseline recording following a sham injection procedure.
    1 context sentence
    Summary · context
    Synthetic delta sleep-inducing peptide (DSIP) was injected intracerebroventricularly into rats in a dose of 7 nmol/kg.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    9 Oct 2026, 18:17 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 03:04 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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