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Study · Animal study (in vivo) · rat · 1983

3 results

Delta-sleep-inducing peptide (DSIP) as a factor facilitating animals' resistance to acute emotional stress.

Sudakov KV, Ivanov VT, Koplik EV, Vedjaev DF, Michaleva II, Sargsjan AS

The Pavlovian journal of biological science1 Jan 1983Cited by 23 (Europe PMC)

PMID6687936 (opens in a new tab)DOI10.1007/bf03004904 (opens in a new tab)PepBankPUB-06687936
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study3

3 results from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Efficacy outcome

    In rats under acute emotional stress, DSIP injections increased resistance to the stress.

    In plain wordsIn rats, DSIP injections increased resistance to acute emotional stress.

    Peptide
    Delta sleep-inducing peptide (DSIP)
    Outcome
    IncreaseResistance to acute emotional stress
    Study

    ratn: not reported in source

    Acute emotional stress by electric stimulation of ventromedial hypothalamus and skin of immobilized rats
    Outcome group
    Anxiety and mood · Mental health and mood
    Studied dose
    Dose not stated

    Source sentences

    Summary
    It is shown that DSIP injections increase animals' resistance to acute emotional stress.
    2 context sentences
    Summary · context
    Delta-sleep-inducing peptide (DSIP) effects on resistance to acute emotional stress induced by electric stimulation of the ventromedial hypothalamus and skin of immobilized rats have been investigated.
    Summary · context
    On the basis of the pattern of cardiovascular reactions, three groups of rats were distinguished: resistant, adapted, and predisposed to the experimental emotional stress.
  2. 02AnimalAnimal study (in vivo)Efficacy outcome

    In rats, DSIP changed vascular reactivity to episodic emotiogenic stimulations.

    In plain wordsIn rats, DSIP changed how blood vessels reacted to repeated emotional stimulation.

    Peptide
    Delta sleep-inducing peptide (DSIP)
    Outcome
    MixedVascular reactivity to emotiogenic stimulation
    Study

    ratn: not reported in source

    Acute emotional stress by electric stimulation of ventromedial hypothalamus and skin of immobilized rats
    Outcome group
    Vascular function · Cardiovascular
    Studied dose
    Dose not stated

    Source sentences

    Summary
    DSIP also changes the vascular reactivity to episodic emotiogenic stimulations.
    2 context sentences
    Summary · context
    Delta-sleep-inducing peptide (DSIP) effects on resistance to acute emotional stress induced by electric stimulation of the ventromedial hypothalamus and skin of immobilized rats have been investigated.
    Summary · context
    On the basis of the pattern of cardiovascular reactions, three groups of rats were distinguished: resistant, adapted, and predisposed to the experimental emotional stress.
  3. 03AnimalAnimal study (in vivo)Efficacy outcome

    In rats, after DSIP application the absence of vascular reactions to ventromedial hypothalamic and electro-skin stimulation increased significantly.

    In plain wordsIn rats, after DSIP, the absence of blood vessel reactions to stress stimulation became significantly more common.

    Peptide
    Delta sleep-inducing peptide (DSIP)
    Outcome
    IncreaseAbsence of vascular reactions to hypothalamic and skin stimulation
    Study

    ratn: not reported in source

    Acute emotional stress by electric stimulation of ventromedial hypothalamus and skin of immobilized rats
    Outcome group
    Vascular function · Cardiovascular
    Studied dose
    Dose not stated

    Source sentences

    Summary
    It is revealed that, after DSIP application, the absence of vascular reactions to emotiogenic ventromedial hypothalamic and electro-skin stimulations significantly increased.
    2 context sentences
    Summary · context
    Delta-sleep-inducing peptide (DSIP) effects on resistance to acute emotional stress induced by electric stimulation of the ventromedial hypothalamus and skin of immobilized rats have been investigated.
    Summary · context
    On the basis of the pattern of cardiovascular reactions, three groups of rats were distinguished: resistant, adapted, and predisposed to the experimental emotional stress.

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Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    10 Oct 2026, 09:43 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 03:04 UTC

    First added · source update from Europe PMC

Subjects

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