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Study · Animal study (in vivo) · mouse · 1983

2 results

Thymic hormone containing cells. III. Evidence for a feed-back regulation of the secretion of the serum thymic factor (FTS) by thymic epithelial cells.

Savino W, Dardenne M, Bach JF

Clinical and experimental immunology1 Apr 1983Cited by 27 (Europe PMC)

PMID6683135 (opens in a new tab)PepBankPUB-06683135
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

1 result from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Mechanism

    In mice, thymulin injections did not significantly depress FTS secretion.

    In plain wordsIn mice, thymulin injections did not significantly reduce FTS secretion.

    Peptide
    Thymulin (serum thymic factor)
    Outcome
    No significant changeFTS secretion
    Study

    mousen: not reported in source

    Mice with altered circulating FTS
    Outcome group
    Immune response · Immune and inflammation
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Injections of thymulin did not significantly depress FTS secretion.
    2 context sentences
    Summary · context
    or FTS enriched by multiple injections of synthetic thymulin (FTS-Zn).
    Summary · context
    Cells containing the serum thymic factor (FTS), as measured by indirect immunofluorescence, were studied in mice either FTS depleted by injection of anti-FTS monoclonal antibodies or immunization against FTS coupled to bovine serum albumin (FTS-BSA),

Natural levels measured1

These results measure the body's own peptide. Nobody was given the peptide. They are not evidence about taking it. They are left out of key results, evidence counts and charts.

  1. 02AnimalEndogenous levelAnimal study (in vivo)Mechanism

    In mice, prolonged elimination of circulating FTS increased thymic intracellular FTS content, indicated by more FTS-containing cells.

    In plain wordsIn mice, removal of circulating natural FTS increased its content in thymus cells.

    Peptide
    Thymulin (serum thymic factor)
    Outcome
    IncreaseThymic intracellular FTS content
    Study

    mousen: not reported in source

    Mice with altered circulating FTS
    Outcome group
    Immune response · Immune and inflammation

    Source sentences

    Summary
    Conversely, long term elimination of FTS from peripheral blood caused a great increase in the thymic intracellular content of FTS, as evidenced by the higher number of FTS containing cells observed with immunofluorescence.
    1 context sentence
    Summary · context
    Cells containing the serum thymic factor (FTS), as measured by indirect immunofluorescence, were studied in mice either FTS depleted by injection of anti-FTS monoclonal antibodies or immunization against FTS coupled to bovine serum albumin (FTS-BSA),

    This result measures the body's own Thymulin (serum thymic factor). Nobody was given the peptide. It is not evidence about taking it.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    21 Oct 2026, 15:58 UTC

    Study results updated

  2. Version 1

    21 Oct 2026, 12:50 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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