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Study · Measured the body's own peptide · 1983

3 results

Plasma concentration of vasoactive intestinal polypeptide during prolonged physical exercise, calorie supply deficiency, and sleep deprivation.

Oktedalen O, Opstad PK, Fahrenkrug J, Fonnum F

Scandinavian journal of gastroenterology1 Nov 1983Cited by 21 (Europe PMC)

PMID6673075 (opens in a new tab)DOI10.3109/00365528309181840 (opens in a new tab)PepBankPUB-06673075
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study3

No result from this study comes from a test of the peptide.

Natural levels measured3

These results measure the body's own peptide. Nobody was given the peptide. They are not evidence about taking it. They are left out of key results, evidence counts and charts.

  1. 01HumanEndogenous levelObservational studyOther

    In military cadets during a 5-day course of exercise, calorie deficiency and sleep deprivation, fasting plasma VIP rose two- to five-fold, with the highest rise on day 2.

    In plain wordsIn cadets under heavy exercise, little food and little sleep, the body's own VIP in blood rose two to five times.

    Peptide
    Vasoactive intestinal peptide (VIP, aviptadil)
    Outcome
    IncreaseFasting plasma VIP during exercise, calorie deficiency and sleep deprivation
    Study

    n = 24

    Outcome group
    Endogenous peptide levels · Endocrine and hormones

    Source sentences

    Summary
    Fasting plasma concentration of VIP increased two- to five-fold during the course, with the highest increase on day 2.
    1 context sentence
    Summary · context
    Twenty-four military cadets went through a 5-day period of heavy physical exercise (35% of max O2 uptake), severe calorie supply deficiency (about 36,000 kJ/24 h), and sleep deprivation (2 h of sleep as a total during 5 days).

    This result measures the body's own Vasoactive intestinal peptide (VIP, aviptadil). Nobody was given the peptide. It is not evidence about taking it.

  2. 02HumanEndogenous levelObservational studyOther

    In military cadets, those who compensated for the calorie deficit had a smaller rise in fasting plasma VIP than those with no calorie or sleep compensation.

    In plain wordsIn cadets, those who made up their calorie shortfall had a smaller rise in the body's own VIP than those who did not.

    Peptide
    Vasoactive intestinal peptide (VIP, aviptadil)
    Outcome
    DecreaseFasting plasma VIP rise in calorie-compensated cadets
    Study

    n: not reported in source

    Comparator
    Cadets with no calorie or sleep compensation
    Outcome group
    Endogenous peptide levels · Endocrine and hormones

    Source sentences

    Summary
    The calorie-compensated subjects showed a smaller increase than those who did not receive any calorie or sleep compensation.
    1 context sentence
    Summary · context
    Twenty-four military cadets went through a 5-day period of heavy physical exercise (35% of max O2 uptake), severe calorie supply deficiency (about 36,000 kJ/24 h), and sleep deprivation (2 h of sleep as a total during 5 days).

    This result measures the body's own Vasoactive intestinal peptide (VIP, aviptadil). Nobody was given the peptide. It is not evidence about taking it.

  3. 03HumanEndogenous levelObservational studyOther

    In military cadets, a meal or glucose solution lowered plasma VIP within 30-60 min to the concentrations of control experiments.

    In plain wordsIn cadets, eating a meal or taking glucose brought the body's own VIP in blood back down within 30 to 60 minutes.

    Peptide
    Vasoactive intestinal peptide (VIP, aviptadil)
    Outcome
    DecreasePlasma VIP after a meal or glucose solution
    Study

    n: not reported in source

    Outcome group
    Endogenous peptide levels · Endocrine and hormones

    Source sentences

    Summary
    Intake of a meal or glucose solution lowered the VIP concentration in plasma within 30-60 min to the concentrations found in the control experiments performed several weeks after the course.
    1 context sentence
    Summary · context
    Twenty-four military cadets went through a 5-day period of heavy physical exercise (35% of max O2 uptake), severe calorie supply deficiency (about 36,000 kJ/24 h), and sleep deprivation (2 h of sleep as a total during 5 days).

    This result measures the body's own Vasoactive intestinal peptide (VIP, aviptadil). Nobody was given the peptide. It is not evidence about taking it.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    12 Oct 2026, 12:58 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 12:41 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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