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Study · Non-randomized trial · n = 4 · 1983

2 results

Calcitonin in the treatment of intractable pain from advanced malignancy.

Allan E

Pharmatherapeutica1 Jan 1983Cited by 13 (Europe PMC)

PMID6669591 (opens in a new tab)PepBankPUB-06669591
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

2 results from studies that gave the peptide. 2 results from people.

  1. 01HumanNon-randomized trialEfficacy outcome

    In patients with malignant bone pain, both salmon calcitonin recipients experienced pain relief, while both placebo recipients did not.

    In plain wordsIn patients with malignant bone pain, both salmon calcitonin recipients had pain relief, while both placebo recipients did not.

    Peptide
    Calcitonin-salmon
    Outcome
    IncreasePain relief in double-blind pilot trial
    Study

    n = 4

    Comparator
    Placebo
    Outcome group
    Pain · Nervous system and cognition
    Studied dose
    200 i.u. twice daily · intramuscular · 4 daysAs given in this study (human).

    Measurements

    Patients with pain relief
    2 patients
    salmon calcitonin
    Patients without pain relief
    2 patients
    placebo

    Source sentences

    Summary
    Two of these patients experienced pain relief and were found to have been given salmon calcitonin; the other 2 had no pain relief and had been given placebo.
    2 context sentences
    Summary · context
    Four of the patients were included in a double-blind pilot trial designed to compare the effectiveness of salmon calcitonin (200 i.u. intramuscularly) and placebo given twice daily for 4 days.
    Summary · context
    Clinical details are given of 8 patients who complained of severe pain from metastatic bone disease or from multiple myeloma.
  2. 02HumanCase report or seriesEfficacy outcome

    In four additional patients with malignant bone pain, salmon calcitonin provided pain relief.

    In plain wordsIn four additional patients with malignant bone pain, salmon calcitonin provided pain relief.

    Peptide
    Calcitonin-salmon
    Outcome
    IncreasePain relief in additional patients
    Study

    n = 4

    Outcome group
    Pain · Nervous system and cognition
    Studied dose
    Dose not stated

    Measurements

    Patients with pain relief
    4 patients
    salmon calcitonin

    Source sentences

    Summary
    The other 4 of the 8 patients were treated with salmon calcitonin and also had relief of their pain.
    1 context sentence
    Summary · context
    Clinical details are given of 8 patients who complained of severe pain from metastatic bone disease or from multiple myeloma.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    28 Oct 2026, 02:03 UTC

    Study results updated

  2. Version 1

    27 Oct 2026, 16:35 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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