Presence of vasopressin, oxytocin and neurophysin in the retina of mammals, effect of light and darkness, comparison with the neuropeptide content of the neurohypophysis and the pineal gland.

Gauquelin G, Geelen G, Louis F, Allevard AM, Meunier C, Cuisinaud G, Benjanet S, Seidah NG, Chretien M, Legros JJ

Peptides1 Jul 1983Cited by 19 (Europe PMC)

PMID6647119DOI10.1016/0196-9781(83)90056-6PepBankPUB-06647119

Publisher page PubMedAsk about this study

Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study4

No result from this study comes from a test of the peptide.

Natural levels measured4

These results measure the body's own peptide. Nobody was given the peptide. They are not evidence about taking it. They are left out of key results, evidence counts and charts.

01LabEndogenous levelEx vivo tissueOther
In rat, human, and bovine retinal tissue, endogenous oxytocin was detected by radioimmunoassay; its presence was confirmed on HPLC fractions in rat and human retinae.
In plain wordsIn lab tests, natural oxytocin was detected in rat, human, and bovine retina; HPLC confirmed it in rat and human retina.
Peptide
Oxytocin
Outcome
Not applicableOxytocin detection in retina
Study
rat, human, and bovinen: not reported in source
retinal tissue
Outcome group
Hormone levels · Eye
Source sentences
Summary
the contents of these neuropeptides in rat, human and bovine retinae were determined. AVP, OT and Np were detected by specific radioimmunoassay (RIA) and their presence confirmed by RIA measurements (1) in rat and human retinae on HPLC fractions
This result measures the body's own Oxytocin. Nobody was given the peptide. It is not evidence about taking it.
Report a problemFND-0664711901
02LabEndogenous levelEx vivo tissueOther
In rat retina, endogenous oxytocin content was lower at 2 a.m. than at 2 p.m.
In plain wordsIn lab tests of rat retinal tissue, the body's own oxytocin was lower at 2 a.m. than at 2 p.m.
Peptide
Oxytocin
Outcome
DecreaseRetinal oxytocin content at 2 a.m. versus 2 p.m.
Study
ratn: not reported in source
retinal tissue
Comparator
2 p.m.
Outcome group
Hormone levels · Eye
Source sentences
Summary
The AVP and OT content in the retina of the rat was modified by light: AVP and OT content was smaller at 2 a.m. than at 2 p.m., but was increased by a 7 day constant exposure to darkness.
This result measures the body's own Oxytocin. Nobody was given the peptide. It is not evidence about taking it.
Report a problemFND-0664711902
03LabEndogenous levelEx vivo tissueOther
In rat retina, 7 days of constant darkness increased endogenous oxytocin content.
In plain wordsIn lab tests of rat retinal tissue, 7 days of constant darkness increased the body's own oxytocin.
Peptide
Oxytocin
Outcome
IncreaseRetinal oxytocin content after constant darkness
Study
ratn: not reported in source
retinal tissue
Outcome group
Hormone levels · Eye
Source sentences
Summary
The AVP and OT content in the retina of the rat was modified by light: AVP and OT content was smaller at 2 a.m. than at 2 p.m., but was increased by a 7 day constant exposure to darkness.
This result measures the body's own Oxytocin. Nobody was given the peptide. It is not evidence about taking it.
Report a problemFND-0664711903
04LabEndogenous levelEx vivo tissueOther
In rat pituitary tissue, endogenous oxytocin content decreased after 7 days of constant darkness.
In plain wordsIn lab tests of rat pituitary tissue, 7 days of constant darkness lowered the body's own oxytocin.
Peptide
Oxytocin
Outcome
DecreasePituitary oxytocin content after constant darkness
Study
ratn: not reported in source
pituitary tissue
Outcome group
Hormone levels · Endocrine and hormones
Source sentences
Summary
The AVP and OT content in the retina of the rat was modified by light: AVP and OT content was smaller at 2 a.m. than at 2 p.m., but was increased by a 7 day constant exposure to darkness. In contrast, pituitary content was decreased after 7 days of constant darkness.
This result measures the body's own Oxytocin. Nobody was given the peptide. It is not evidence about taking it.
Report a problemFND-0664711904

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Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

Version 2Current
11 Oct 2026, 20:03 UTC
Study results updated
Version 1
9 Oct 2026, 02:53 UTC
First added · source update from Europe PMC

Subjects

Terms as the source lists them.

Publication types

MeSH terms

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