Skip to content

Study · Measured the body's own peptide · 1983

4 results

Thymosin alpha 1-like peptides: localization and biochemical characterization in the rat brain and pituitary gland.

Palaszynski EW, Moody TW, O'Donohue TL, Goldstein AL

Peptides1 Jul 1983Cited by 19 (Europe PMC)

PMID6647116 (opens in a new tab)DOI10.1016/0196-9781(83)90050-5 (opens in a new tab)PepBankPUB-06647116
Publisher pagePubMedAsk about this study
Jump to 4 results

Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study4

No result from this study comes from a test of the peptide.

Natural levels measured4

These results measure the body's own peptide. Nobody was given the peptide. They are not evidence about taking it. They are left out of key results, evidence counts and charts.

  1. 01AnimalEndogenous levelAnimal study (in vivo)Other

    In rats, thymosin alpha‑1-like peptides were present in high concentrations in hypothalamus and pituitary extracts.

    In plain wordsIn rats, the body's own thymosin alpha‑1-like peptides were found at high levels in the hypothalamus and pituitary gland.

    Peptide
    Thymosin alpha-1
    Outcome
    Not applicableThymosin alpha 1-like peptide concentration in hypothalamus and pituitary
    Study

    ratn: not reported in source

    brain and pituitary extracts
    Outcome group
    Endogenous peptide levels · Nervous system and cognition

    Source sentences

    Summary
    Thymosin alpha 1-like peptides were present in high concentrations in hypothalamus and pituitary extracts.
    1 context sentence
    Summary · context
    Using a radioimmunoassay for thymosin alpha 1, endogenous thymosin-like peptides were characterized in the rat brain and pituitary gland.

    This result measures the body's own Thymosin alpha-1. Nobody was given the peptide. It is not evidence about taking it.

  2. 02AnimalEndogenous levelAnimal study (in vivo)Other

    In rats, immunoreactive thymosin was densest in the median eminence, the arcuate nucleus of the hypothalamus and the neurointermediate lobe of the pituitary.

    In plain wordsIn rats, the body's own thymosin alpha‑1-like peptides were most dense in a few hypothalamus and pituitary regions.

    Peptide
    Thymosin alpha-1
    Outcome
    Not applicableRegional distribution of immunoreactive thymosin in brain and pituitary
    Study

    ratn: not reported in source

    brain and pituitary extracts
    Outcome group
    Endogenous peptide levels · Nervous system and cognition

    Source sentences

    Summary
    The discrete regional distribution of thymosin alpha 1-like peptides was investigated and the highest densities of immunoreactive thymosin were present in the median eminence and arcuate nucleus of the hypothalamus, as well as the neurointermediate lobe of the pituitary.
    1 context sentence
    Summary · context
    Using a radioimmunoassay for thymosin alpha 1, endogenous thymosin-like peptides were characterized in the rat brain and pituitary gland.

    This result measures the body's own Thymosin alpha-1. Nobody was given the peptide. It is not evidence about taking it.

  3. 03AnimalEndogenous levelAnimal study (in vivo)Other

    In rat brain and pituitary extracts, the main immunoreactive thymosin peak had a molecular weight similar to that of thymosin alpha‑1.

    In plain wordsIn rats, the main natural thymosin-like peptide in brain and pituitary had a size similar to thymosin alpha‑1.

    Peptide
    Thymosin alpha-1
    Outcome
    Not applicableMolecular weight of main immunoreactive thymosin peak
    Study

    ratn: not reported in source

    brain and pituitary extracts
    Outcome group
    Endogenous peptide levels · Nervous system and cognition

    Source sentences

    Summary
    These peptides were characterized using gel filtration techniques and the main peak of immunoreactive thymosin had a molecular weight similar to that of thymosin alpha 1 (3108 daltons).
    1 context sentence
    Summary · context
    Using a radioimmunoassay for thymosin alpha 1, endogenous thymosin-like peptides were characterized in the rat brain and pituitary gland.

    This result measures the body's own Thymosin alpha-1. Nobody was given the peptide. It is not evidence about taking it.

  4. 04AnimalEndogenous levelAnimal study (in vivo)Other

    In rats, HPLC showed one main immunoreactive peak in brain extracts and two in pituitary extracts, one of which coeluted with thymosin alpha‑1.

    In plain wordsIn rats, one natural thymosin-like peak was in brain extracts and two in pituitary extracts; one matched thymosin alpha‑1.

    Peptide
    Thymosin alpha-1
    Outcome
    Not applicableHPLC profile of immunoreactive thymosin
    Study

    ratn: not reported in source

    brain and pituitary extracts
    Outcome group
    Endogenous peptide levels · Nervous system and cognition

    Source sentences

    Summary
    Using HPLC techniques, one main peak of immunoreactivity was present in brain extracts, whereas two peaks were present in pituitary extracts, one of which coeluted with thymosin alpha 1.
    1 context sentence
    Summary · context
    Using a radioimmunoassay for thymosin alpha 1, endogenous thymosin-like peptides were characterized in the rat brain and pituitary gland.

    This result measures the body's own Thymosin alpha-1. Nobody was given the peptide. It is not evidence about taking it.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 3Current

    10 Oct 2026, 08:55 UTC

    Study results updated

  2. Version 2

    9 Oct 2026, 03:03 UTC

    Study data updated · source update from Europe PMC

  3. Version 1

    9 Oct 2026, 03:02 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

PepBank is a research reference. Talk to a doctor before you use any peptide.