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Study · Measured the body's own peptide · 1983

4 results

Familial central diabetes insipidus: vasopressin and nicotine stimulated neurophysin deficiency with subnormal oxytocin and estrogen stimulated neurophysin.

Blackett PR, Seif SM, Altmiller DH, Robinson AG

The American journal of the medical sciences1 Nov 1983Cited by 6 (Europe PMC)

PMID6638059 (opens in a new tab)DOI10.1097/00000441-198311000-00007 (opens in a new tab)PepBankPUB-06638059
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study4

No result from this study comes from a test of the peptide.

Natural levels measured3

These results measure the body's own peptide. Nobody was given the peptide. They are not evidence about taking it. They are left out of key results, evidence counts and charts.

  1. 01HumanEndogenous levelCase report or seriesOther

    In two people with familial central diabetes insipidus, endogenous oxytocin was unstimulated after cigarette inhalation.

    In plain wordsIn two people, the body's own oxytocin did not rise after cigarette inhalation.

    Peptide
    Oxytocin
    Outcome
    No significant changeOxytocin response to cigarette inhalation
    Study

    n = 2

    Outcome group
    Hormone levels · Endocrine and hormones

    Source sentences

    Summary
    Levels of oxytocin (OT) were found to be normal and unstimulated after cigarette inhalation in two subjects, but when two affected male siblings ingested Ovulen, OT and ESN were stimulated to subnormal levels.

    This result measures the body's own Oxytocin. Nobody was given the peptide. It is not evidence about taking it.

  2. 02HumanEndogenous levelCase report or seriesOther

    In two affected male siblings, Ovulen ingestion stimulated endogenous oxytocin to subnormal levels.

    In plain wordsIn two men, Ovulen stimulated the body's own oxytocin, but levels remained below normal.

    Peptide
    Oxytocin
    Outcome
    IncreaseOxytocin response after Ovulen ingestion
    Study

    n = 2

    Outcome group
    Hormone levels · Endocrine and hormones

    Source sentences

    Summary
    Levels of oxytocin (OT) were found to be normal and unstimulated after cigarette inhalation in two subjects, but when two affected male siblings ingested Ovulen, OT and ESN were stimulated to subnormal levels.

    This result measures the body's own Oxytocin. Nobody was given the peptide. It is not evidence about taking it.

  3. 03HumanEndogenous levelCase report or seriesOther

    In two people with familial central diabetes insipidus, endogenous oxytocin levels were normal after cigarette inhalation.

    In plain wordsIn two people, the body's own oxytocin levels were normal after cigarette inhalation.

    Peptide
    Oxytocin
    Outcome
    Not applicableOxytocin level after cigarette inhalation
    Study

    n = 2

    Outcome group
    Hormone levels · Endocrine and hormones

    Source sentences

    Summary
    Levels of oxytocin (OT) were found to be normal and unstimulated after cigarette inhalation in two subjects, but when two affected male siblings ingested Ovulen, OT and ESN were stimulated to subnormal levels.

    This result measures the body's own Oxytocin. Nobody was given the peptide. It is not evidence about taking it.

Studies that did not test the peptide alone1

In this study, Oxytocin was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking Oxytocin.

  1. 04HumanNot a test of Oxytocin aloneCase report or seriesOther

    In two affected male siblings, Ovulen ingestion stimulated estrogen-stimulated neurophysin to subnormal levels.

    In plain wordsIn two men, Ovulen increased estrogen-stimulated neurophysin, but levels remained below normal.

    Peptide
    Oxytocin
    Outcome
    IncreaseEstrogen-stimulated neurophysin response after Ovulen ingestion
    Study

    n = 2

    Outcome group
    Hormone levels · Endocrine and hormones

    Source sentences

    Summary
    Levels of oxytocin (OT) were found to be normal and unstimulated after cigarette inhalation in two subjects, but when two affected male siblings ingested Ovulen, OT and ESN were stimulated to subnormal levels.
    1 context sentence
    Title · context
    Familial central diabetes insipidus: vasopressin and nicotine stimulated neurophysin deficiency with subnormal oxytocin and estrogen stimulated neurophysin.

    In this study, Oxytocin was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Oxytocin.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    11 Oct 2026, 20:03 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 02:53 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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