Isolation of thymosin alpha 1 from thymosin fraction 5 of different species by high-performance liquid chromatography.

Low TL, McClure JE, Naylor PH, Spangelo BL, Goldstein AL

Journal of chromatography1 Aug 1983Cited by 17 (Europe PMC)

PMID6630360DOI10.1016/s0021-9673(01)90924-0PepBankPUB-06630360

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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

No result from this study comes from a test of the peptide.

Natural levels measured1

These results measure the body's own peptide. Nobody was given the peptide. They are not evidence about taking it. They are left out of key results, evidence counts and charts.

01AnimalEndogenous levelAnimal study (in vivo)Other
In fresh thymus tissue extracts, HPLC did not reveal a detectable protein or immunoreactive peak at the thymosin alpha‑1 position.
In plain wordsIn fresh animal thymus extracts, no peak of the body's own thymosin alpha‑1 was detected.
Peptide
Thymosin alpha-1
Outcome
No significant changeThymosin alpha 1 peak in fresh thymus tissue extracts
Study
animaln: not reported in source
fresh thymus tissue extracts
Outcome group
Endogenous peptide levels · Pharmacology
Source sentences
Summary
Chromatographic analysis of fresh thymus tissue extracts using a high-performance liquid chromatographic similar system did not reveal a detectable protein peak or immunoreactive peak at the alpha 1 position.
This result measures the body's own Thymosin alpha-1. Nobody was given the peptide. It is not evidence about taking it.
Report a problemFND-0663036002

Studies that did not test the peptide alone1

In this study, Thymosin alpha-1 was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking Thymosin alpha-1.

02LabNot a test of Thymosin alpha-1 aloneIn vitro (cell-free)Other
By HPLC, thymosin fraction 5 from calf, pig, sheep and mouse each gave a peak with retention time similar to bovine thymosin alpha‑1 that coincided with the radioimmunoassay peak.
In plain wordsIn lab tests, thymosin fraction 5 from four animal species each contained a peak matching thymosin alpha‑1.
Peptide
Thymosin alpha-1
Outcome
Not applicableHPLC isolation of thymosin alpha 1 from thymosin fraction 5 of several species
Study
calf, pig, sheep, mousen: not reported in source
thymosin fraction 5 preparations
Outcome group
Endogenous peptide levels · Pharmacology
Source sentences
Summary
Each of the f5 preparations gave a protein peak similar in retention time to bovine thymosin alpha 1. This peak coincided with the immunoreactive peak determined by a radioimmunoassay for alpha 1.
In this study, Thymosin alpha-1 was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Thymosin alpha-1.
Report a problemFND-0663036001

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

Version 3Current
10 Oct 2026, 08:55 UTC
Study results updated
Version 2
9 Oct 2026, 03:03 UTC
Study data updated · source update from Europe PMC
Version 1
9 Oct 2026, 03:02 UTC
First added · source update from Europe PMC