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Study · Ex vivo tissue · 1983

3 results

Biochemical and immunological differentiation of human thymocytes induced by thymic hormones.

Ho AD, Ma DD, Price G, Hunstein W, Hoffbrand AV

Immunology1 Nov 1983Cited by 21 (Europe PMC)

PMID6605305 (opens in a new tab)PepBankPUB-06605305

Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study3

3 results from studies that gave the peptide. No result from this study comes from people.

  1. 01LabEx vivo tissueEfficacy outcome

    In human thymocytes, thymosin alpha‑1 lowered terminal deoxynucleotidyl transferase (TdT) activity.

    In plain wordsIn lab tests on human thymus cells, thymosin alpha‑1 lowered TdT enzyme activity.

    Outcome
    DecreaseTdT activity in human thymocytes
    Study

    humann: not reported in source

    human thymocytes
    Outcome group
    Immune response · Immune and inflammation
    Studied dose
    Dose not stated

    Source sentences

    Summary
    TMS-alpha 1 a fall in TdT and ADA activities
    1 context sentence
    Summary · context
    We have investigated the effects of four thymic factors: thymosin fraction 5 (TMS-F5); thymosin alpha 1 (TMS-alpha 1)
  2. 02LabEx vivo tissueEfficacy outcome

    In human thymocytes, thymosin alpha‑1 lowered adenosine deaminase (ADA) activity.

    In plain wordsIn lab tests on human thymus cells, thymosin alpha‑1 lowered ADA enzyme activity.

    Outcome
    DecreaseADA activity in human thymocytes
    Study

    humann: not reported in source

    human thymocytes
    Outcome group
    Immune response · Immune and inflammation
    Studied dose
    Dose not stated

    Source sentences

    Summary
    TMS-alpha 1 a fall in TdT and ADA activities
    1 context sentence
    Summary · context
    We have investigated the effects of four thymic factors: thymosin fraction 5 (TMS-F5); thymosin alpha 1 (TMS-alpha 1)
  3. 03LabEx vivo tissueEfficacy outcome

    In human thymocytes, thymosin alpha‑1 raised the number of OKT3-positive (mature T) cells.

    In plain wordsIn lab tests on human thymus cells, thymosin alpha‑1 raised the number of mature T cells.

    Outcome
    IncreaseOKT3-positive cells in human thymocytes
    Study

    humann: not reported in source

    human thymocytes
    Outcome group
    Immune response · Immune and inflammation
    Studied dose
    Dose not stated

    Source sentences

    Summary
    a rise in OKT3-positive cells
    1 context sentence
    Summary · context
    We have investigated the effects of four thymic factors: thymosin fraction 5 (TMS-F5); thymosin alpha 1 (TMS-alpha 1)

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 3Current

    10 Oct 2026, 08:55 UTC

    Study results updated

  2. Version 2

    9 Oct 2026, 03:03 UTC

    Study data updated · source update from Europe PMC

  3. Version 1

    9 Oct 2026, 03:02 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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