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Study · Measured the body's own peptide · 1984

2 results

Distribution of prothymosin alpha in rat tissues.

Haritos AA, Tsolas O, Horecker BL

Proceedings of the National Academy of Sciences of the United States of America1 Mar 1984Cited by 89 (Europe PMC)

PMID6584887 (opens in a new tab)PMCIDPMC344840 (opens in a new tab)DOI10.1073/pnas.81.5.1391 (opens in a new tab)PepBankPUB-06584887
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

No result from this study comes from a test of the peptide.

Natural levels measured2

These results measure the body's own peptide. Nobody was given the peptide. They are not evidence about taking it. They are left out of key results, evidence counts and charts.

  1. 01AnimalEndogenous levelAnimal study (in vivo)Other

    In rats, thymosin alpha‑1 cross-reacting material was highest in thymus and was also present in brain, liver, kidney, lung and spleen at 15% to 65% of the thymus amount.

    In plain wordsIn rats, the body's own material that reacts like thymosin alpha‑1 was found in several organs, at 15% to 65% of the thymus amount.

    Peptide
    Thymosin alpha-1
    Outcome
    Direction not reportedThymosin alpha 1 cross-reacting material in non-thymic tissues
    Study

    ratn: not reported in source

    Outcome group
    Immune response · Whole body

    Measurements

    Cross-reacting material relative to thymus
    15 to 65%
    brain, liver, kidney, lung, spleen

    Source sentences

    Summary
    Highest concentrations were present in thymus, but thymosin alpha 1 cross-reacting material was also detected in brain, liver, kidney, lung, and spleen, in amounts ranging from 15% to 65% of the quantities found in thymus.
    1 context sentence
    Summary · context
    A radioimmunoassay, using a rabbit antiserum directed against thymosin alpha 1, was employed to detect the presence of crossreacting peptides in rat tissues.

    This result measures the body's own Thymosin alpha-1. Nobody was given the peptide. It is not evidence about taking it.

  2. 02AnimalEndogenous levelAnimal study (in vivo)Other

    In rat tissue extracts, no peptides corresponding in size and chromatographic behavior to thymosin alpha‑1 were detected.

    In plain wordsIn rats, tissue extracts held no free peptide of thymosin alpha‑1 size; the body's own cross-reacting material was a larger peptide.

    Peptide
    Thymosin alpha-1
    Outcome
    No significant changeThymosin alpha 1-sized peptide in rat tissue extracts
    Study

    ratn: not reported in source

    Outcome group
    Immune response · Whole body

    Source sentences

    Summary
    No peptides corresponding in size and chromatographic behavior to thymosin alpha 1 were detected with the extraction procedure employed.
    2 context sentences
    Summary · context
    In each case, the major immunoreactive peptide, after extraction and purification by a procedure that avoids proteolytic modification, was identified as prothymosin alpha, a peptide containing approximately equal to 112 amino acid residues.
    Summary · context
    A radioimmunoassay, using a rabbit antiserum directed against thymosin alpha 1, was employed to detect the presence of crossreacting peptides in rat tissues.

    This result measures the body's own Thymosin alpha-1. Nobody was given the peptide. It is not evidence about taking it.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 3Current

    10 Oct 2026, 08:55 UTC

    Study results updated

  2. Version 2

    9 Oct 2026, 03:03 UTC

    Study data updated · source update from Europe PMC

  3. Version 1

    9 Oct 2026, 03:02 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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