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Study · Measured the body's own peptide · 1984

4 results

DSIP occurs in free form in mammalian plasma, human CSF and urine.

Graf MV, Kastin AJ, Fischman AJ

Pharmacology, biochemistry, and behavior1 Nov 1984Cited by 18 (Europe PMC)

PMID6549071 (opens in a new tab)DOI10.1016/s0091-3057(84)80016-7 (opens in a new tab)PepBankPUB-06549071
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study4

No result from this study comes from a test of the peptide.

Natural levels measured4

These results measure the body's own peptide. Nobody was given the peptide. They are not evidence about taking it. They are left out of key results, evidence counts and charts.

  1. 01HumanEndogenous levelObservational studyOther

    In human plasma, gel chromatography and HPLC showed a distinct peak of DSIP-like immunoreactivity at the elution position of synthetic DSIP.

    In plain wordsThe body's own free DSIP was found in human blood plasma.

    Peptide
    Delta sleep-inducing peptide (DSIP)
    Outcome
    Not applicableFree DSIP-like immunoreactivity in human plasma
    Study

    n: not reported in source

    Outcome group
    Sleep · Sleep

    Source sentences

    Summary
    Using gel chromatography (Sephadex G-100) and subsequent high performance liquid chromatography on rabbit, human, rat and dog plasma, we now show a distinct peak of DSIP-LI that has the same elution position as synthetic DSIP.

    This result measures the body's own Delta sleep-inducing peptide (DSIP). Nobody was given the peptide. It is not evidence about taking it.

  2. 02HumanEndogenous levelObservational studyOther

    Free DSIP was also found in human cerebrospinal fluid.

    In plain wordsThe body's own free DSIP was also found in human spinal fluid.

    Peptide
    Delta sleep-inducing peptide (DSIP)
    Outcome
    Not applicableFree DSIP in human cerebrospinal fluid
    Study

    n: not reported in source

    Outcome group
    Sleep · Sleep

    Source sentences

    Summary
    Free DSIP was also found in human CSF

    This result measures the body's own Delta sleep-inducing peptide (DSIP). Nobody was given the peptide. It is not evidence about taking it.

  3. 03HumanEndogenous levelObservational studyOther

    In human urine, most small molecular weight DSIP-like immunoreactivity eluted at the position of the phosphorylated analog DSIP-P.

    In plain wordsIn human urine, most of the body's own small DSIP-like material was the phosphorylated form of DSIP.

    Peptide
    Delta sleep-inducing peptide (DSIP)
    Outcome
    Not applicableDSIP-like immunoreactivity in human urine
    Study

    n: not reported in source

    Outcome group
    Sleep · Sleep

    Source sentences

    Summary
    whereas in human urine most of the small molecular weight DSIP-LI eluted at a position corresponding to DSIP-P, the phosphorylated analog of DSIP.

    This result measures the body's own Delta sleep-inducing peptide (DSIP). Nobody was given the peptide. It is not evidence about taking it.

  4. 04AnimalEndogenous levelAnimal study (in vivo)Other

    In rabbit, rat and dog plasma, gel chromatography and HPLC showed a distinct peak of DSIP-like immunoreactivity at the elution position of synthetic DSIP.

    In plain wordsIn rabbits, rats and dogs, the body's own free DSIP was found in blood plasma.

    Peptide
    Delta sleep-inducing peptide (DSIP)
    Outcome
    Not applicableFree DSIP-like immunoreactivity in animal plasma
    Study

    rabbit, rat, dogn: not reported in source

    Plasma
    Outcome group
    Sleep · Sleep

    Source sentences

    Summary
    Using gel chromatography (Sephadex G-100) and subsequent high performance liquid chromatography on rabbit, human, rat and dog plasma, we now show a distinct peak of DSIP-LI that has the same elution position as synthetic DSIP.

    This result measures the body's own Delta sleep-inducing peptide (DSIP). Nobody was given the peptide. It is not evidence about taking it.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    10 Oct 2026, 09:43 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 03:04 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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