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Study · Measured the body's own peptide · 1984

2 results

Delta sleep-inducing peptide-like material in rat brain as determined by enzyme immunoassay: effect of sleep deprivation.

Nagaki S, Kato N

Neuroscience letters1 Oct 1984Cited by 7 (Europe PMC)

PMID6549054 (opens in a new tab)DOI10.1016/0304-3940(84)90560-3 (opens in a new tab)PepBankPUB-06549054
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

No result from this study comes from a test of the peptide.

Natural levels measured2

These results measure the body's own peptide. Nobody was given the peptide. They are not evidence about taking it. They are left out of key results, evidence counts and charts.

  1. 01AnimalEndogenous levelAnimal study (in vivo)Other

    In rat brain, immunoreactive DSIP was more concentrated in limbic structures, although contents were generally low.

    In plain wordsIn rats, the body's own DSIP-like material was found mostly in the brain's limbic areas, at low levels.

    Peptide
    Delta sleep-inducing peptide (DSIP)
    Outcome
    Not applicableRegional distribution of immunoreactive DSIP in rat brain
    Study

    ratn: not reported in source

    rat brain, enzyme immunoassay
    Outcome group
    Endogenous peptide levels · Nervous system and cognition

    Source sentences

    Summary
    IR-DSIP proved to be more concentrated in the limbic structures, although the contents were generally at a low level.
    1 context sentence
    Summary · context
    The regional distribution of immunoreactive delta sleep-inducing peptide (IR-DSIP) and the effect of 24-h sleep deprivation on the IR-DSIP content was investigated in the rat brain by means of enzyme immunoassay (EIA) of the assayable IR-DSIP in the rat brain coeluted with authentic DSIP in the gel filtration.

    This result measures the body's own Delta sleep-inducing peptide (DSIP). Nobody was given the peptide. It is not evidence about taking it.

  2. 02AnimalEndogenous levelAnimal study (in vivo)Other

    In rats, 24-hour sleep deprivation and rebound sleep did not significantly change brain contents of free-form DSIP.

    In plain wordsIn rats, going without sleep for 24 hours did not significantly change the body's own free DSIP in the brain.

    Peptide
    Delta sleep-inducing peptide (DSIP)
    Outcome
    No significant changeEffect of 24-h sleep deprivation and rebound sleep on free DSIP content
    Study

    ratn: not reported in source

    rat brain, enzyme immunoassay
    Outcome group
    Sleep · Sleep

    Source sentences

    Summary
    Sleep deprivation and subsequent rebound sleep had no significant effect on the brain contents of 'free-form' DSIP.
    1 context sentence
    Summary · context
    The regional distribution of immunoreactive delta sleep-inducing peptide (IR-DSIP) and the effect of 24-h sleep deprivation on the IR-DSIP content was investigated in the rat brain by means of enzyme immunoassay (EIA) of the assayable IR-DSIP in the rat brain coeluted with authentic DSIP in the gel filtration.

    This result measures the body's own Delta sleep-inducing peptide (DSIP). Nobody was given the peptide. It is not evidence about taking it.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    10 Oct 2026, 09:43 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 03:04 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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