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Study · In vitro (cells) · rat · 1984

2 results

Cellular localization of binding sites for 3H-DSIP on neurones of cultured rat brain stem.

Hösli E, Schoenenberger GA, Hösli L

European neurology1 Jan 1984Cited by 2 (Europe PMC)

PMID6548965 (opens in a new tab)DOI10.1159/000115710 (opens in a new tab)PepBankPUB-06548965
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

2 results from studies that gave the peptide. No result from this study comes from people.

  1. 01LabIn vitro (cells)Activity measurement

    In cultured rat brain stem cells, 3H-DSIP binding sites were seen on neuronal soma and processes but not on glial cells.

    In plain wordsIn cells, labelled DSIP bound to brain stem neurones but not to glial cells.

    Peptide
    Delta sleep-inducing peptide (DSIP)
    Outcome
    Not applicable3H-DSIP binding sites on neurones versus glial cells
    Study

    ratn: not reported in source

    cultured rat brain stem neurones
    Outcome group
    Receptor activity and mechanism · Nervous system and cognition
    Studied dose
    Dose not stated

    Source sentences

    Summary
    By means of light-microscopic autoradiography, binding sites for the delta sleep-inducing peptide (3H-DSIP) were observed on the soma and processes of cultured brain stem neurones but not on glial cells.
  2. 02LabIn vitro (cells)Activity measurement

    In cultured rat brain stem neurones, unlabelled DSIP at high concentrations inhibited 3H-DSIP binding, indicating specific binding.

    In plain wordsIn cells, a high amount of unlabelled DSIP reduced the binding of labelled DSIP, which points to specific binding.

    Peptide
    Delta sleep-inducing peptide (DSIP)
    Outcome
    Not applicableInhibition of 3H-DSIP binding by unlabelled DSIP
    Study

    ratn: not reported in source

    cultured rat brain stem neurones
    Outcome group
    Receptor activity and mechanism · Nervous system and cognition
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Unlabelled DSIP at high concentrations inhibited binding of 3H-DSIP, indicating specific binding of this peptide.
    1 context sentence
    Summary · context
    By means of light-microscopic autoradiography, binding sites for the delta sleep-inducing peptide (3H-DSIP) were observed on the soma and processes of cultured brain stem neurones but not on glial cells.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    10 Oct 2026, 09:43 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 03:04 UTC

    First added · source update from Europe PMC

Subjects

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