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Study · Animal study (in vivo) · rat · 1984

2 results

Modification of the hypothermic circadian cycles induced by DSIP and melatonin in pinealectomized and hypophysectomized rats.

Yehuda S, Mostofsky DI

Peptides1 May 1984Cited by 13 (Europe PMC)

PMID6548024 (opens in a new tab)DOI10.1016/0196-9781(84)90076-7 (opens in a new tab)PepBankPUB-06548024
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

2 results from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Efficacy outcome

    In intact rats, the hypothermic effect of DSIP depended on the circadian cycle.

    In plain wordsIn intact rats, how much DSIP lowered body temperature depended on the time of day.

    Peptide
    Delta sleep-inducing peptide (DSIP)
    Outcome
    Not applicableCircadian dependence of DSIP hypothermic effect in intact rats
    Study

    ratn: not reported in source

    intact, pinealectomized and hypophysectomized rats
    Outcome group
    Body temperature · Whole body
    Studied dose
    Dose not stated

    Source sentences

    Summary
    While both DSIP and melatonin hypothermic effects were both circadian cycle dependent in intact rats
    1 context sentence
    Summary · context
    In this study we report the hypothermia effects by each of these drugs alone and in combination when studied in normal (unoperated), pinealectomized, and hypophysectomized rats at various time points of the corresponding circadian cycle.
  2. 02AnimalAnimal study (in vivo)Efficacy outcome

    In hypophysectomized rats, the circadian rhythm of the hypothermic effect of DSIP was missing.

    In plain wordsIn rats without a pituitary gland, the daily rhythm in DSIP's temperature-lowering effect was missing.

    Peptide
    Delta sleep-inducing peptide (DSIP)
    Outcome
    Not applicableCircadian rhythm of DSIP hypothermic effect in hypophysectomized rats
    Study

    ratn: not reported in source

    intact, pinealectomized and hypophysectomized rats
    Outcome group
    Body temperature · Whole body
    Studied dose
    Dose not stated

    Source sentences

    Summary
    DSIP hypothermic effect in hypophysectomized rats was missing.
    1 context sentence
    Summary · context
    In this study we report the hypothermia effects by each of these drugs alone and in combination when studied in normal (unoperated), pinealectomized, and hypophysectomized rats at various time points of the corresponding circadian cycle.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    10 Oct 2026, 09:43 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 03:04 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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