Skip to content

Study · Animal study (in vivo) · rabbit · 1984

4 results

[Hypnogenic properties of the delta-sleep peptide and its structural analogs].

Aliautdin RN, Kalikhevich VN, Churkina VI

Farmakologiia i toksikologiia1 May 1984Cited by 1 (Europe PMC)

PMID6547392 (opens in a new tab)PepBankPUB-06547392
Publisher pageAsk about this study
Jump to 4 results

Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study4

2 results from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Efficacy outcome

    In unrestrained rabbits, intraventricular DSIP (60 micrograms) produced sleep lasting 55-65 minutes.

    In plain wordsIn rabbits, DSIP injected into the brain ventricles produced sleep lasting 55-65 minutes.

    Peptide
    Delta sleep-inducing peptide (DSIP)
    Outcome
    IncreaseSleep duration
    Study

    rabbitn: not reported in source

    Outcome group
    Sleep · Sleep
    Studied dose
    60 micrograms · intraventricularAs given in this study (rabbit).

    Measurements

    Sleep duration
    55 to 65 min
    rabbits, DSIP 60 micrograms

    Source sentences

    Summary
    It has been demonstrated in unrestrained rabbits that the delta-sleep-inducing peptide (DSIP, 60 micrograms, intraventricularly) produced sleep lasting 55-65 min.
  2. 02AnimalAnimal study (in vivo)Efficacy outcome

    In unrestrained rabbits, during DSIP-induced sleep the amount of EEG delta-waves was 230% of the initial level.

    In plain wordsIn rabbits, during DSIP-induced sleep, brain delta waves rose to 230% of the starting level.

    Peptide
    Delta sleep-inducing peptide (DSIP)
    Outcome
    IncreaseEEG delta-wave amount
    Study

    rabbitn: not reported in source

    Outcome group
    Sleep · Sleep
    Studied dose
    60 micrograms · intraventricularAs given in this study (rabbit).

    Measurements

    Delta-wave amount
    230 % of initial level
    rabbits, DSIP 60 micrograms

    Source sentences

    Summary
    At that time the amount of delta-waves on the EEG was 230 % of the initial level.
    1 context sentence
    Summary · context
    It has been demonstrated in unrestrained rabbits that the delta-sleep-inducing peptide (DSIP, 60 micrograms, intraventricularly) produced sleep lasting 55-65 min.

Studies that did not test the peptide alone2

In this study, Delta sleep-inducing peptide (DSIP) was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking Delta sleep-inducing peptide (DSIP).

  1. 03AnimalNot a test of Delta sleep-inducing peptide (DSIP) aloneAnimal study (in vivo)Efficacy outcome

    In rabbits, the DPhe-containing analogue, of 22 DSIP analogues tested, compared favourably with DSIP in hypnogenic activity.

    In plain wordsIn rabbits, one DSIP-like compound with DPhe was about as active in inducing sleep as DSIP.

    Peptide
    Delta sleep-inducing peptide (DSIP)
    Outcome
    No significant changeHypnogenic activity of DPhe-containing DSIP analogue
    Study

    rabbitn: not reported in source

    Comparator
    DSIP
    Outcome group
    Sleep · Sleep

    Source sentences

    Summary
    Of the 22 structural analogs of DSIP, the DPhe-containing compound compared favourably with the delta-sleep-inducing peptide as regards the activity.

    In this study, Delta sleep-inducing peptide (DSIP) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Delta sleep-inducing peptide (DSIP).

  2. 04AnimalNot a test of Delta sleep-inducing peptide (DSIP) aloneAnimal study (in vivo)Efficacy outcome

    In rabbits, the other DSIP analogues were either less active than DSIP or had no hypnogenic activity.

    In plain wordsIn rabbits, the other DSIP-like compounds were less active than DSIP or did not induce sleep.

    Peptide
    Delta sleep-inducing peptide (DSIP)
    Outcome
    DecreaseHypnogenic activity of other DSIP analogues
    Study

    rabbitn: not reported in source

    Comparator
    DSIP
    Outcome group
    Sleep · Sleep

    Source sentences

    Summary
    Other analogs were either less active or had no hypnogenic activity at all.

    In this study, Delta sleep-inducing peptide (DSIP) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Delta sleep-inducing peptide (DSIP).

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    12 Oct 2026, 17:28 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 03:04 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

PepBank is a research reference. Talk to a doctor before you use any peptide.