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Study · Animal study (in vivo) · rat · 1984

2 results

Haemodynamic effects of arginine-vasopressin microinjections into the nucleus tractus solitarius: a comparative study of vasopressin, a selective vasopressin receptor agonist and antagonist, and oxytocin.

Vallejo M, Carter DA, Lightman SL

Neuroscience letters1 Dec 1984Cited by 44 (Europe PMC)

PMID6521969 (opens in a new tab)DOI10.1016/0304-3940(84)90169-1 (opens in a new tab)PepBankPUB-06521969
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

2 results from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Efficacy outcome

    In rats, oxytocin microinjection did not produce the rise in mean arterial pressure seen with vasopressin.

    In plain wordsIn rats, oxytocin did not raise mean arterial pressure like vasopressin.

    Peptide
    Oxytocin
    Outcome
    No significant changeMean arterial pressure
    Study

    ratn: not reported in source

    nucleus tractus solitarius
    Comparator
    Vasopressin
    Outcome group
    Blood pressure · Cardiovascular
    Studied dose
    Dose not stated · microinjectionAs given in this study (rat).

    Source sentences

    Summary
    Arginine-vasopressin (AVP) and related peptides were administered by microinjection into the nucleus tractus solitarius of the rat. AVP produced a rise both in mean arterial pressure and in heart rate. This effect was abolished by pretreatment with a specific antagonist of V1 receptors and was not s…
  2. 02AnimalAnimal study (in vivo)Efficacy outcome

    In rats, oxytocin microinjection did not produce the heart-rate rise seen with vasopressin.

    In plain wordsIn rats, oxytocin did not raise heart rate like vasopressin.

    Peptide
    Oxytocin
    Outcome
    No significant changeHeart rate
    Study

    ratn: not reported in source

    nucleus tractus solitarius
    Comparator
    Vasopressin
    Outcome group
    Heart function · Cardiovascular
    Studied dose
    Dose not stated · microinjectionAs given in this study (rat).

    Source sentences

    Summary
    Arginine-vasopressin (AVP) and related peptides were administered by microinjection into the nucleus tractus solitarius of the rat. AVP produced a rise both in mean arterial pressure and in heart rate. This effect was abolished by pretreatment with a specific antagonist of V1 receptors and was not s…

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Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    11 Oct 2026, 20:03 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 02:52 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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