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Study · Ex vivo tissue · frog · 1984

2 results

Cellular pH and the ADH-induced hydrosmotic response in different ADH target epithelia.

Parisi M, Wietzerbin J

Pflugers Archiv : European journal of physiology1 Oct 1984Cited by 6 (Europe PMC)

PMID6441925 (opens in a new tab)DOI10.1007/bf00583337 (opens in a new tab)PepBankPUB-06441925
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

1 result from studies that gave the peptide. No result from this study comes from people.

  1. 01LabEx vivo tissueActivity measurement

    In isolated frog skin epithelium, oxytocin increased intracellular pH.

    In plain wordsIn lab tests with isolated frog skin, oxytocin increased intracellular pH.

    Peptide
    Oxytocin
    Outcome
    IncreaseIntracellular pH in isolated skin epithelium
    Study

    frogn: not reported in source

    isolated frog skin epithelium
    Outcome group
    Receptor activity and mechanism · Pharmacology
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Incubation with oxytocin also augmented the intracellular pH in the isolated frog skin epithelium but 8 Br-CAMP did not modify cell proton concentration in this tissue.
    1 context sentence
    Summary · context
    In other experiments intracellular pH was measured, employing the dimetyl-oxazolidine-dione distribution technique, in frog urinary bladder and the isolated frog skin epithelium.

Studies that did not test the peptide alone1

In this study, Oxytocin was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking Oxytocin.

  1. 02LabNot a test of Oxytocin aloneEx vivo tissueActivity measurement

    In frog skin epithelium, medium acidification reversibly inhibited the hydrosmotic response elicited by oxytocin by 70%.

    In plain wordsIn lab tests with frog skin, reducing medium pH to 6.2 reversibly reduced the oxytocin-elicited water response by 70%.

    Peptide
    Oxytocin
    Outcome
    DecreaseHydrosmotic response during medium acidification
    Study

    frogn: not reported in source

    isolated frog skin epithelium
    Outcome group
    Electrolyte balance · Pharmacology

    Measurements

    Hydrosmotic response inhibition
    70%
    medium pH reduced to 6.2 by CO2 bubbling

    Source sentences

    Summary
    The hydrosmotic response elicited by oxytocin in the frog skin epithelium (Rana esculenta) was reversibly inhibited by 70% when the medium pH was reduced to 6.2 by CO2 bubbling on the serosal side.
    1 context sentence
    Summary · context
    In other experiments intracellular pH was measured, employing the dimetyl-oxazolidine-dione distribution technique, in frog urinary bladder and the isolated frog skin epithelium.

    In this study, Oxytocin was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Oxytocin.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    11 Oct 2026, 20:03 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 02:53 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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