Skip to content

Study · Ex vivo tissue · toad · 1984

5 results

An osmometric method for the bioassay of vasotocin and related peptides in the toad bladder.

Eggena P

Endocrinology1 Dec 1984Cited by 5 (Europe PMC)

PMID6437792 (opens in a new tab)DOI10.1210/endo-115-6-2104 (opens in a new tab)PepBankPUB-06437792
Publisher pagePubMedAsk about this study
Jump to 5 results

Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study5

5 results from studies that gave the peptide. No result from this study comes from people.

  1. 01LabEx vivo tissueActivity measurement

    In isolated toad urinary bladder, oxytocin produced a maximal hydroosmotic response similar to 8-arginine vasotocin.

    In plain wordsIn isolated toad bladder tissue, oxytocin produced a water-response similar to 8-arginine vasotocin.

    Peptide
    Oxytocin
    Outcome
    Not applicableMaximal hydroosmotic response
    Study

    toadn: not reported in source

    isolated urinary bladder
    Comparator
    8-arginine vasotocin
    Outcome group
    Electrolyte balance · Pharmacology
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Similar maximal responses were observed with 8-arginine vasopressin (AVP), oxytocin, and 8-lysine vasopressin, although the potencies of these hormones diminished in the order listed above.
    2 context sentences
    Summary · context
    A supramaximal dose of AVT reduced disc fluid osmolality by 188 mosmol/kg H2O within 15 min.
    Summary · context
    This study describes a new method for quantitating the antidiuretic activity of 8-arginine vasotocin (AVT) and related peptides on the isolated toad urinary bladder.
  2. 02LabEx vivo tissueActivity measurement

    In isolated toad urinary bladder, oxytocin had lower hydroosmotic potency than 8-arginine vasopressin.

    In plain wordsIn isolated toad bladder tissue, oxytocin was less potent than 8-arginine vasopressin.

    Peptide
    Oxytocin
    Outcome
    DecreaseHydroosmotic potency versus arginine vasopressin
    Study

    toadn: not reported in source

    isolated urinary bladder
    Comparator
    8-arginine vasopressin
    Outcome group
    Electrolyte balance · Pharmacology
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Similar maximal responses were observed with 8-arginine vasopressin (AVP), oxytocin, and 8-lysine vasopressin, although the potencies of these hormones diminished in the order listed above.
    1 context sentence
    Summary · context
    This study describes a new method for quantitating the antidiuretic activity of 8-arginine vasotocin (AVT) and related peptides on the isolated toad urinary bladder.
  3. 03LabEx vivo tissueActivity measurement

    In isolated toad urinary bladder, oxytocin had greater hydroosmotic potency than 8-lysine vasopressin.

    In plain wordsIn isolated toad bladder tissue, oxytocin was more potent than 8-lysine vasopressin.

    Peptide
    Oxytocin
    Outcome
    IncreaseHydroosmotic potency versus 8-lysine vasopressin
    Study

    toadn: not reported in source

    isolated urinary bladder
    Comparator
    8-lysine vasopressin
    Outcome group
    Electrolyte balance · Pharmacology
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Similar maximal responses were observed with 8-arginine vasopressin (AVP), oxytocin, and 8-lysine vasopressin, although the potencies of these hormones diminished in the order listed above.
    1 context sentence
    Summary · context
    This study describes a new method for quantitating the antidiuretic activity of 8-arginine vasotocin (AVT) and related peptides on the isolated toad urinary bladder.
  4. 04LabEx vivo tissueActivity measurement

    In isolated toad urinary bladder, oxytocin produced a maximal hydroosmotic response similar to 8-arginine vasopressin.

    In plain wordsIn isolated toad bladder tissue, oxytocin produced a water response similar to 8-arginine vasopressin.

    Peptide
    Oxytocin
    Outcome
    Not applicableMaximal hydroosmotic response
    Study

    toadn: not reported in source

    isolated urinary bladder
    Comparator
    8-arginine vasopressin
    Outcome group
    Electrolyte balance · Pharmacology
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Similar maximal responses were observed with 8-arginine vasopressin (AVP), oxytocin, and 8-lysine vasopressin, although the potencies of these hormones diminished in the order listed above.
  5. 05LabEx vivo tissueActivity measurement

    In isolated toad urinary bladder, oxytocin produced a maximal hydroosmotic response similar to 8-lysine vasopressin.

    In plain wordsIn isolated toad bladder tissue, oxytocin produced a water response similar to 8-lysine vasopressin.

    Peptide
    Oxytocin
    Outcome
    Not applicableMaximal hydroosmotic response
    Study

    toadn: not reported in source

    isolated urinary bladder
    Comparator
    8-lysine vasopressin
    Outcome group
    Electrolyte balance · Pharmacology
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Similar maximal responses were observed with 8-arginine vasopressin (AVP), oxytocin, and 8-lysine vasopressin, although the potencies of these hormones diminished in the order listed above.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    11 Oct 2026, 20:03 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 02:54 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

PepBank is a research reference. Talk to a doctor before you use any peptide.