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Study · Animal study (in vivo) · mouse · 1983

4 results

Alloreactivity. I. Effects of age and thymic hormone treatment on cell-mediated immunity in C57B1/6NNia mice.

Ghanta VK, Noble PJ, Brown ME, Cox PJ, Hiramoto NS, Hiramoto RN

Mechanisms of ageing and development1 Jul 1983Cited by 5 (Europe PMC)

PMID6415352 (opens in a new tab)DOI10.1016/0047-6374(83)90085-4 (opens in a new tab)PepBankPUB-06415352
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study4

4 results from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Activity measurement

    In one-month-old mice, FTS significantly increased cell-mediated cytotoxicity compared with physiological saline.

    In plain wordsIn young mice, FTS increased cell-mediated cytotoxicity compared with saline.

    Peptide
    Thymulin (serum thymic factor)
    Outcome
    IncreaseCell-mediated cytotoxicity
    Study

    mousen: not reported in source

    C57B1/6NNia mice
    Comparator
    Physiological saline
    Outcome group
    Immune response · Immune and inflammation
    Studied dose
    1 microgram/mouseAs given in this study (mouse).

    Source sentences

    Summary
    When cytotoxicity of the thymic hormone treated groups was compared to that of the physiological saline treated group, 1-month-old mice treated with serum thymic factor (FTS) at 1 microgram/mouse and 10 ng/mouse had significantly higher activity, and lower to similar activities at 12 and 24 months;
  2. 02AnimalAnimal study (in vivo)Activity measurement

    In one-month-old mice, FTS significantly increased cell-mediated cytotoxicity compared with physiological saline.

    In plain wordsIn young mice, FTS increased cell-mediated cytotoxicity compared with saline.

    Peptide
    Thymulin (serum thymic factor)
    Outcome
    IncreaseCell-mediated cytotoxicity
    Study

    mousen: not reported in source

    C57B1/6NNia mice
    Comparator
    Physiological saline
    Outcome group
    Immune response · Immune and inflammation
    Studied dose
    10 ng/mouseAs given in this study (mouse).

    Source sentences

    Summary
    When cytotoxicity of the thymic hormone treated groups was compared to that of the physiological saline treated group, 1-month-old mice treated with serum thymic factor (FTS) at 1 microgram/mouse and 10 ng/mouse had significantly higher activity, and lower to similar activities at 12 and 24 months;
  3. 03AnimalAnimal study (in vivo)Activity measurement

    In twelve-month-old mice, FTS produced lower to similar cytotoxicity compared with physiological saline.

    In plain wordsIn middle-aged mice, FTS produced lower to similar cell-mediated cytotoxicity compared with saline.

    Peptide
    Thymulin (serum thymic factor)
    Outcome
    MixedCell-mediated cytotoxicity
    Study

    mousen: not reported in source

    C57B1/6NNia mice
    Comparator
    Physiological saline
    Outcome group
    Immune response · Immune and inflammation
    Studied dose
    1 microgram/mouse and 10 ng/mouseAs given in this study (mouse).

    Source sentences

    Summary
    When cytotoxicity of the thymic hormone treated groups was compared to that of the physiological saline treated group, 1-month-old mice treated with serum thymic factor (FTS) at 1 microgram/mouse and 10 ng/mouse had significantly higher activity, and lower to similar activities at 12 and 24 months;
  4. 04AnimalAnimal study (in vivo)Activity measurement

    In twenty-four-month-old mice, FTS produced lower to similar cytotoxicity compared with physiological saline.

    In plain wordsIn aged mice, FTS produced lower to similar cell-mediated cytotoxicity compared with saline.

    Peptide
    Thymulin (serum thymic factor)
    Outcome
    MixedCell-mediated cytotoxicity
    Study

    mousen: not reported in source

    C57B1/6NNia mice
    Comparator
    Physiological saline
    Outcome group
    Immune response · Immune and inflammation
    Studied dose
    1 microgram/mouse and 10 ng/mouseAs given in this study (mouse).

    Source sentences

    Summary
    When cytotoxicity of the thymic hormone treated groups was compared to that of the physiological saline treated group, 1-month-old mice treated with serum thymic factor (FTS) at 1 microgram/mouse and 10 ng/mouse had significantly higher activity, and lower to similar activities at 12 and 24 months;

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    21 Oct 2026, 15:58 UTC

    Study results updated

  2. Version 1

    21 Oct 2026, 12:50 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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