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Study · Measured the body's own peptide · 1983

2 results

Vasoactive intestinal polypeptide-like immunoreactive nerves in diabetic penis. A comparison between streptozotocin-treated rats and man.

Crowe R, Lincoln J, Blacklay PF, Pryor JP, Lumley JS, Burnstock G

Diabetes1 Nov 1983Cited by 48 (Europe PMC)

PMID6357906 (opens in a new tab)DOI10.2337/diab.32.11.1075 (opens in a new tab)PepBankPUB-06357906
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

No result from this study comes from a test of the peptide.

Natural levels measured2

These results measure the body's own peptide. Nobody was given the peptide. They are not evidence about taking it. They are left out of key results, evidence counts and charts.

  1. 01HumanEndogenous levelCase report or seriesMechanism

    In one diabetic man with impotence, VIP-like immunoreactivity in penile nerves was reduced.

    In plain wordsIn one diabetic man with impotence, nerves in penile tissue held less of the body's own VIP.

    Peptide
    Vasoactive intestinal peptide (VIP, aviptadil)
    Outcome
    DecreaseVIP-like immunoreactivity in penile nerves of a diabetic man with impotence
    Study

    n = 1

    Outcome group
    Endogenous peptide levels · Reproductive and sexual health

    Source sentences

    Summary
    A reduction in VIP-like immunoreactivity in nerves was revealed in tissue from streptozotocin-diabetic rats and a human diabetic with impotence.

    This result measures the body's own Vasoactive intestinal peptide (VIP, aviptadil). Nobody was given the peptide. It is not evidence about taking it.

  2. 02AnimalEndogenous levelAnimal study (in vivo)Mechanism

    In streptozotocin-diabetic rats, VIP-like immunoreactivity in penile nerves was reduced.

    In plain wordsIn diabetic rats, nerves in penile tissue held less of the body's own VIP.

    Peptide
    Vasoactive intestinal peptide (VIP, aviptadil)
    Outcome
    DecreaseVIP-like immunoreactivity in penile nerves of diabetic rats
    Study

    ratn: not reported in source

    streptozotocin-diabetic rat penile tissue
    Outcome group
    Endogenous peptide levels · Reproductive and sexual health

    Source sentences

    Summary
    A reduction in VIP-like immunoreactivity in nerves was revealed in tissue from streptozotocin-diabetic rats and a human diabetic with impotence.

    This result measures the body's own Vasoactive intestinal peptide (VIP, aviptadil). Nobody was given the peptide. It is not evidence about taking it.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    12 Oct 2026, 12:58 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 12:41 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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