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Study · Ex vivo tissue · frog · 1984

6 results

The onset and offset of the hydrosmotic response in frog epithelia.

Parisi M, Lacaz-Vieira F, Wietzerbin J, Bourguet J

Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas1 Jan 1984

PMID6335667 (opens in a new tab)PepBankPUB-06335667
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study6

3 results from studies that gave the peptide. No result from this study comes from people.

  1. 01LabEx vivo tissueActivity measurement

    In frog skin, the offset of oxytocin's hydrosmotic action was slower than in urinary bladder.

    In plain wordsIn lab tests with frog skin, the oxytocin water response ended more slowly than in urinary bladder.

    Peptide
    Oxytocin
    Outcome
    DecreaseOffset speed of hydrosmotic response versus urinary bladder
    Study

    frogn: not reported in source

    frog skin epithelium
    Comparator
    urinary bladder
    Outcome group
    Electrolyte balance · Pharmacology
    Studied dose
    Dose not stated

    Source sentences

    Summary
    The offset of these actions was not affected by corion removal and was also slower than in the bladder.
    2 context sentences
    Summary · context
    The removal of the frog skin supporting layers accelerated the onset of the reactions to oxytocin and 8-bromo-cyclic AMP (8-Br-cAMP), which, however, remained slower than the onset in the urinary bladder.
    Summary · context
    The onset and offset of the hydrosmotic responses elicited by different agonists in frog urinary bladder, frog skin and isolated frog skin epithelium were studied and compared.
  2. 02LabEx vivo tissueActivity measurement

    In frog skin, oxytocin increased water permeability.

    In plain wordsIn lab tests with frog skin, oxytocin increased water permeability.

    Peptide
    Oxytocin
    Outcome
    IncreaseWater permeability
    Study

    frogn: not reported in source

    frog skin
    Outcome group
    Electrolyte balance · Pharmacology
    Studied dose
    Dose not stated

    Source sentences

    Summary
    The results show that the increases in water permeability elicited by oxytocin and cyclic-AMP derivatives in frog skin and frog urinary bladder
    1 context sentence
    Summary · context
    The onset and offset of the hydrosmotic responses elicited by different agonists in frog urinary bladder, frog skin and isolated frog skin epithelium were studied and compared.
  3. 03LabEx vivo tissueActivity measurement

    In frog urinary bladder, oxytocin increased water permeability.

    In plain wordsIn lab tests with frog urinary bladder, oxytocin increased water permeability.

    Peptide
    Oxytocin
    Outcome
    IncreaseWater permeability
    Study

    frogn: not reported in source

    urinary bladder
    Outcome group
    Electrolyte balance · Pharmacology
    Studied dose
    Dose not stated

    Source sentences

    Summary
    The results show that the increases in water permeability elicited by oxytocin and cyclic-AMP derivatives in frog skin and frog urinary bladder
    1 context sentence
    Summary · context
    The onset and offset of the hydrosmotic responses elicited by different agonists in frog urinary bladder, frog skin and isolated frog skin epithelium were studied and compared.

Studies that did not test the peptide alone3

In this study, Oxytocin was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking Oxytocin.

  1. 04LabNot a test of Oxytocin aloneEx vivo tissueActivity measurement

    In frog skin, removal of supporting layers accelerated the onset of the hydrosmotic response to oxytocin.

    In plain wordsIn lab tests with frog skin, removing supporting layers made the oxytocin water-permeability response start faster.

    Peptide
    Oxytocin
    Outcome
    IncreaseOnset of hydrosmotic response after supporting-layer removal
    Study

    frogn: not reported in source

    frog skin epithelium
    Outcome group
    Electrolyte balance · Pharmacology

    Source sentences

    Summary
    The removal of the frog skin supporting layers accelerated the onset of the reactions to oxytocin and 8-bromo-cyclic AMP (8-Br-cAMP), which, however, remained slower than the onset in the urinary bladder.
    1 context sentence
    Summary · context
    The onset and offset of the hydrosmotic responses elicited by different agonists in frog urinary bladder, frog skin and isolated frog skin epithelium were studied and compared.

    In this study, Oxytocin was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Oxytocin.

  2. 05LabNot a test of Oxytocin aloneEx vivo tissueActivity measurement

    In frog skin, corion removal did not affect the offset of oxytocin's hydrosmotic action.

    In plain wordsIn lab tests with frog skin, corion removal did not change how the oxytocin water-permeability response ended.

    Peptide
    Oxytocin
    Outcome
    No significant changeOffset of hydrosmotic response after corion removal
    Study

    frogn: not reported in source

    frog skin epithelium
    Outcome group
    Electrolyte balance · Pharmacology

    Source sentences

    Summary
    The offset of these actions was not affected by corion removal and was also slower than in the bladder.
    2 context sentences
    Summary · context
    The removal of the frog skin supporting layers accelerated the onset of the reactions to oxytocin and 8-bromo-cyclic AMP (8-Br-cAMP), which, however, remained slower than the onset in the urinary bladder.
    Summary · context
    The onset and offset of the hydrosmotic responses elicited by different agonists in frog urinary bladder, frog skin and isolated frog skin epithelium were studied and compared.

    In this study, Oxytocin was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Oxytocin.

  3. 06LabNot a test of Oxytocin aloneEx vivo tissueActivity measurement

    In frog skin with supporting layers removed, oxytocin's hydrosmotic response started more slowly than in urinary bladder.

    In plain wordsIn lab tests with frog skin, oxytocin's water response started more slowly than in urinary bladder.

    Peptide
    Oxytocin
    Outcome
    DecreaseOnset of hydrosmotic response
    Study

    frogn: not reported in source

    frog skin
    Comparator
    urinary bladder
    Outcome group
    Electrolyte balance · Pharmacology

    Source sentences

    Summary
    The removal of the frog skin supporting layers accelerated the onset of the reactions to oxytocin and 8-bromo-cyclic AMP (8-Br-cAMP), which, however, remained slower than the onset in the urinary bladder.

    In this study, Oxytocin was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Oxytocin.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    11 Oct 2026, 20:03 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 02:53 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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