In lymphocyte cultures, adding thymosin alpha‑1 enhanced specific anti-influenza antibody synthesis, to a greater extent in cultures from elderly volunteers.
In plain wordsIn lab cell cultures, thymosin alpha‑1 raised antibody production against influenza, more in cultures from older donors.
- Peptide
- Thymosin alpha-1
- Outcome
- IncreaseSpecific anti-influenza antibody synthesis in lymphocyte cultures from elderly volunteers
- Study
humann: not reported in source
lymphocyte cultures from young and elderly volunteers- Outcome group
- Immune response · Immune and inflammation
- Studied dose
- Dose not stated
Source sentences
the addition of a thymic hormone preparation (either thymosin fraction 5 or thymosin alpha 1) was shown to enhance specific antibody synthesis to a greater extent in the cultures established from the elderly volunteers.
1 context sentence(design, population, supporting numbers)
We measured antibody response to the trivalent 1983-1984 influenza vaccine in young and elderly volunteers and found a significantly reduced response in the latter.