The vasopressor and oxytocic activities of the hypothalamus and neurohypophysis influenced by stimulated alpha-adrenergic transmission during dehydration and subsequent rehydration in the white rat.

Ciosek J, Guzek JW, Morawska J

Acta physiologica Polonica1 May 1983

PMID6326469PepBankPUB-06326469

Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study10

No result from this study comes from a test of the peptide.

Natural levels measured10

These results measure the body's own peptide. Nobody was given the peptide. They are not evidence about taking it. They are left out of key results, evidence counts and charts.

01AnimalEndogenous levelAnimal study (in vivo)Other
In rats under equilibrated water metabolism, methoxamine increased hypothalamic oxytocin content.
In plain wordsIn rats, methoxamine increased the body's own oxytocin in the hypothalamus under equilibrated water metabolism.
Peptide
Oxytocin
Outcome
IncreaseHypothalamic oxytocin content after methoxamine under equilibrated water metabolism
Study
white ratn: not reported in source
hypothalamus and neurohypophysis
Outcome group
Endogenous peptide levels · Endocrine and hormones
Source sentences
Summary
Under conditions of equilibrated water metabolism a single dose of methoxamine increased the content of vasopressin in the hypothalamus as well as that of oxytocin both in the hypothalamus and neurohypophysis.
This result measures the body's own Oxytocin. Nobody was given the peptide. It is not evidence about taking it.
Report a problemFND-0632646901
02AnimalEndogenous levelAnimal study (in vivo)Other
In rats under equilibrated water metabolism, methoxamine increased neurohypophysial oxytocin content.
In plain wordsIn rats, methoxamine increased the body's own oxytocin in the neurohypophysis under equilibrated water metabolism.
Peptide
Oxytocin
Outcome
IncreaseNeurohypophysial oxytocin content after methoxamine under equilibrated water metabolism
Study
white ratn: not reported in source
hypothalamus and neurohypophysis
Outcome group
Endogenous peptide levels · Endocrine and hormones
Source sentences
Summary
Under conditions of equilibrated water metabolism a single dose of methoxamine increased the content of vasopressin in the hypothalamus as well as that of oxytocin both in the hypothalamus and neurohypophysis.
This result measures the body's own Oxytocin. Nobody was given the peptide. It is not evidence about taking it.
Report a problemFND-0632646902
03AnimalEndogenous levelAnimal study (in vivo)Other
After two days of dehydration in rats, methoxamine inhibited the decrease of hypothalamic oxytocin content.
In plain wordsAfter two days without water, methoxamine preserved the body's own hypothalamic oxytocin in rats.
Peptide
Oxytocin
Outcome
IncreaseHypothalamic oxytocin depletion after two days of dehydration
Study
white ratn: not reported in source
hypothalamus and neurohypophysis
Outcome group
Endogenous peptide levels · Endocrine and hormones
Source sentences
Summary
After two days of dehydration methoxamine inhibited the decrease of oxytocin content in the hypothalamus
This result measures the body's own Oxytocin. Nobody was given the peptide. It is not evidence about taking it.
Report a problemFND-0632646903
04AnimalEndogenous levelAnimal study (in vivo)Other
After two days of dehydration in rats, methoxamine intensified loss of neurohypophysial oxytocin content.
In plain wordsAfter two days without water, methoxamine lowered the body's own neurohypophysial oxytocin in rats.
Peptide
Oxytocin
Outcome
DecreaseNeurohypophysial oxytocin depletion after two days of dehydration
Study
white ratn: not reported in source
hypothalamus and neurohypophysis
Outcome group
Endogenous peptide levels · Endocrine and hormones
Source sentences
Summary
After two days of dehydration methoxamine inhibited the decrease of oxytocin content in the hypothalamus; simultaneously (2nd and 4th day of dehydration) it intensified this process in the neurohypophysis.
This result measures the body's own Oxytocin. Nobody was given the peptide. It is not evidence about taking it.
Report a problemFND-0632646904
05AnimalEndogenous levelAnimal study (in vivo)Other
During rehydration in rats other than on day eight, methoxamine favoured somewhat the renewal of hypothalamic oxytocin.
In plain wordsDuring rehydration except on day eight, methoxamine favoured renewal of the body's own hypothalamic oxytocin in rats.
Peptide
Oxytocin
Outcome
IncreaseHypothalamic oxytocin renewal during rehydration
Study
white ratn: not reported in source
hypothalamus and neurohypophysis
Outcome group
Endogenous peptide levels · Endocrine and hormones
Source sentences
Summary
On the contrary, it favoured somewhat the renewal of hypothalamic oxytocin in rehydrated rats (such an event was not found on the 8th day of rehydration).
This result measures the body's own Oxytocin. Nobody was given the peptide. It is not evidence about taking it.
Report a problemFND-0632646905
06AnimalEndogenous levelAnimal study (in vivo)Other
After two days of rehydration in rats, methoxamine restrained restoration of neurohypophysial oxytocin stores.
In plain wordsAfter two days of rehydration, methoxamine reduced restoration of the body's own neurohypophysial oxytocin in rats.
Peptide
Oxytocin
Outcome
DecreaseNeurohypophysial oxytocin restoration after two days of rehydration
Study
white ratn: not reported in source
hypothalamus and neurohypophysis
Outcome group
Endogenous peptide levels · Endocrine and hormones
Source sentences
Summary
Moreover, methoxamine restrained initially (on the 2nd and 4th day of rehydration) the restoration of neurohypophysial oxytocin stores; following eight days of rehydration an opposite effect was here found.
This result measures the body's own Oxytocin. Nobody was given the peptide. It is not evidence about taking it.
Report a problemFND-0632646906
07AnimalEndogenous levelAnimal study (in vivo)Other
After eight days of rehydration in rats, methoxamine favoured restoration of neurohypophysial oxytocin stores.
In plain wordsAfter eight days of rehydration, methoxamine favoured restoration of the body's own neurohypophysial oxytocin in rats.
Peptide
Oxytocin
Outcome
IncreaseNeurohypophysial oxytocin restoration after eight days of rehydration
Study
white ratn: not reported in source
hypothalamus and neurohypophysis
Outcome group
Endogenous peptide levels · Endocrine and hormones
Source sentences
Summary
Moreover, methoxamine restrained initially (on the 2nd and 4th day of rehydration) the restoration of neurohypophysial oxytocin stores; following eight days of rehydration an opposite effect was here found.
This result measures the body's own Oxytocin. Nobody was given the peptide. It is not evidence about taking it.
Report a problemFND-0632646907
08AnimalEndogenous levelAnimal study (in vivo)Other
On day eight of rehydration in rats, methoxamine did not favour renewal of hypothalamic oxytocin.
In plain wordsOn day eight of rehydration, methoxamine did not favour renewal of the body's own hypothalamic oxytocin in rats.
Peptide
Oxytocin
Outcome
No significant changeHypothalamic oxytocin renewal on day eight of rehydration
Study
white ratn: not reported in source
hypothalamus
Outcome group
Endogenous peptide levels · Endocrine and hormones
Source sentences
Summary
On the contrary, it favoured somewhat the renewal of hypothalamic oxytocin in rehydrated rats (such an event was not found on the 8th day of rehydration).
This result measures the body's own Oxytocin. Nobody was given the peptide. It is not evidence about taking it.
Report a problemFND-0632646908
09AnimalEndogenous levelAnimal study (in vivo)Other
After four days of dehydration in rats, methoxamine intensified loss of neurohypophysial oxytocin content.
In plain wordsAfter four days without water, methoxamine lowered the body's own neurohypophysial oxytocin in rats.
Peptide
Oxytocin
Outcome
DecreaseNeurohypophysial oxytocin depletion after four days of dehydration
Study
white ratn: not reported in source
neurohypophysis
Outcome group
Endogenous peptide levels · Endocrine and hormones
Source sentences
Summary
After two days of dehydration methoxamine inhibited the decrease of oxytocin content in the hypothalamus; simultaneously (2nd and 4th day of dehydration) it intensified this process in the neurohypophysis.
This result measures the body's own Oxytocin. Nobody was given the peptide. It is not evidence about taking it.
Report a problemFND-0632646909
10AnimalEndogenous levelAnimal study (in vivo)Other
After four days of rehydration in rats, methoxamine restrained restoration of neurohypophysial oxytocin stores.
In plain wordsAfter four days of rehydration, methoxamine reduced restoration of the body's own neurohypophysial oxytocin in rats.
Peptide
Oxytocin
Outcome
DecreaseNeurohypophysial oxytocin restoration after four days of rehydration
Study
white ratn: not reported in source
neurohypophysis
Outcome group
Endogenous peptide levels · Endocrine and hormones
Source sentences
Summary
Moreover, methoxamine restrained initially (on the 2nd and 4th day of rehydration) the restoration of neurohypophysial oxytocin stores; following eight days of rehydration an opposite effect was here found.
This result measures the body's own Oxytocin. Nobody was given the peptide. It is not evidence about taking it.
Report a problemFND-0632646910

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

Version 2Current
11 Oct 2026, 20:03 UTC
Study results updated
Version 1
9 Oct 2026, 02:53 UTC
First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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MeSH terms

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