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Study · In vitro (cells) · 1982

3 results

Activities of purine nucleotide metabolizing enzymes in human thymocytes and peripheral blood T lymphocytes: in vitro effect of thymic hormones.

Ramagopal S, Reem GH

Thymus1 May 1982Cited by 7 (Europe PMC)

PMID6287680 (opens in a new tab)PepBankPUB-06287680
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study3

3 results from studies that gave the peptide. No result from this study comes from people.

  1. 01LabIn vitro (cells)Mechanism

    In human thymocyte cultures, FTS had no significant stimulatory or inhibitory effect on adenosine deaminase activity.

    In plain wordsIn cells from the human thymus, FTS did not significantly change adenosine deaminase activity.

    Peptide
    Thymulin (serum thymic factor)
    Outcome
    No significant changeAdenosine deaminase activity
    Study

    humann: not reported in source

    Short-term thymocyte cultures
    Outcome group
    Receptor activity and mechanism · Immune and inflammation
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Exposure of thymocytes in short-term culture to the thymic hormones thymopoietin (the pentapeptide TP5), thymosin fraction V or serum thymic factor (FTS) had no significant stimulatory or inhibitory effect on the activities of the three enzymes under our experimental conditions.
    1 context sentence
    Summary · context
    Adenosine deaminase (ADA, E.C. 3.5.4.4) and purine nucleoside phosphorylase (PNP, E.C. 2.4.2.1)
  2. 02LabIn vitro (cells)Mechanism

    In human thymocyte cultures, FTS had no significant stimulatory or inhibitory effect on purine nucleoside phosphorylase activity.

    In plain wordsIn cells from the human thymus, FTS did not significantly change purine nucleoside phosphorylase activity.

    Peptide
    Thymulin (serum thymic factor)
    Outcome
    No significant changePurine nucleoside phosphorylase activity
    Study

    humann: not reported in source

    Short-term thymocyte cultures
    Outcome group
    Receptor activity and mechanism · Immune and inflammation
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Exposure of thymocytes in short-term culture to the thymic hormones thymopoietin (the pentapeptide TP5), thymosin fraction V or serum thymic factor (FTS) had no significant stimulatory or inhibitory effect on the activities of the three enzymes under our experimental conditions.
    1 context sentence
    Summary · context
    Adenosine deaminase (ADA, E.C. 3.5.4.4) and purine nucleoside phosphorylase (PNP, E.C. 2.4.2.1)
  3. 03LabIn vitro (cells)Mechanism

    In human thymocyte cultures, FTS had no significant stimulatory or inhibitory effect on ecto-5'-nucleotidase activity.

    In plain wordsIn cells from the human thymus, FTS did not significantly change ecto-5'-nucleotidase activity.

    Peptide
    Thymulin (serum thymic factor)
    Outcome
    No significant changeEcto-5'-nucleotidase activity
    Study

    humann: not reported in source

    Short-term thymocyte cultures
    Outcome group
    Receptor activity and mechanism · Immune and inflammation
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Exposure of thymocytes in short-term culture to the thymic hormones thymopoietin (the pentapeptide TP5), thymosin fraction V or serum thymic factor (FTS) had no significant stimulatory or inhibitory effect on the activities of the three enzymes under our experimental conditions.
    1 context sentence
    Summary · context
    A comparison of the specific activity of these two enzymes and of ecto-5'-nucleotidase (5'-N, E.C. 3.1.3.5) of human thymocytes

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    21 Oct 2026, 15:58 UTC

    Study results updated

  2. Version 1

    21 Oct 2026, 12:50 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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